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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFCAB4B
All Species:
13.33
Human Site:
S195
Identified Species:
32.59
UniProt:
Q9BSW2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BSW2
NP_116069.1
395
45592
S195
K
E
E
P
H
L
L
S
N
F
E
D
F
L
T
Chimpanzee
Pan troglodytes
XP_001156341
349
40105
L173
R
L
G
A
Q
K
V
L
E
D
E
S
D
V
K
Rhesus Macaque
Macaca mulatta
XP_001099191
395
45802
S195
K
D
E
P
H
L
L
S
N
F
E
D
F
L
T
Dog
Lupus familis
XP_543866
546
63029
S186
K
D
K
P
H
L
L
S
S
F
E
D
F
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q3UP38
310
35821
G139
E
K
V
Y
Q
S
R
G
E
E
D
V
G
D
M
Rat
Rattus norvegicus
XP_575675
803
91156
S266
K
D
E
P
H
L
L
S
N
F
E
D
L
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P0CB05
711
81982
L202
Q
I
L
E
S
V
E
L
A
S
R
S
E
I
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922837
334
39046
E159
L
G
A
S
N
I
F
E
D
P
E
E
V
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785593
232
26649
E62
E
E
L
E
V
V
C
E
N
L
D
R
D
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
N700
K
A
D
I
A
L
K
N
S
E
T
E
H
L
K
Conservation
Percent
Protein Identity:
100
82.7
96.4
59.5
N.A.
57.7
38.3
N.A.
N.A.
21.2
N.A.
45.3
N.A.
N.A.
N.A.
N.A.
22.5
Protein Similarity:
100
84.3
97.9
63.9
N.A.
66
44.4
N.A.
N.A.
34.3
N.A.
61.7
N.A.
N.A.
N.A.
N.A.
39.2
P-Site Identity:
100
6.6
93.3
80
N.A.
0
86.6
N.A.
N.A.
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
26.6
100
100
N.A.
20
93.3
N.A.
N.A.
20
N.A.
40
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
30
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
10
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
30
10
0
0
0
0
0
10
10
20
40
20
10
0
% D
% Glu:
20
20
30
20
0
0
10
20
20
20
60
20
10
10
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
40
0
0
30
0
0
% F
% Gly:
0
10
10
0
0
0
0
10
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
40
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
0
10
0
10
0
0
0
0
0
0
0
10
0
% I
% Lys:
50
10
10
0
0
10
10
0
0
0
0
0
0
0
20
% K
% Leu:
10
10
20
0
0
50
40
20
0
10
0
0
10
50
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
10
0
0
10
40
0
0
0
0
0
0
% N
% Pro:
0
0
0
40
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
10
0
0
0
20
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
0
0
0
0
0
10
0
0
0
10
10
0
10
0
% R
% Ser:
0
0
0
10
10
10
0
40
20
10
0
20
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
40
% T
% Val:
0
0
10
0
10
20
10
0
0
0
0
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _