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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EFCAB4B All Species: 8.18
Human Site: S388 Identified Species: 20
UniProt: Q9BSW2 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BSW2 NP_116069.1 395 45592 S388 V L R A P P R S L G S E G P V
Chimpanzee Pan troglodytes XP_001156341 349 40105 K342 S L Q Q E A C K L H Q E K E M
Rhesus Macaque Macaca mulatta XP_001099191 395 45802 S388 V L R A P P R S L G S E G P V
Dog Lupus familis XP_543866 546 63029 E485 L S K C P E E E E V S Q Q R V
Cat Felis silvestris
Mouse Mus musculus Q3UP38 310 35821
Rat Rattus norvegicus XP_575675 803 91156 T784 L L K E Q E D T V R K D I I Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P0CB05 711 81982 S666 L C P L P T S S V G S V A A R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922837 334 39046 R327 L L Q E Q S S R L H E E R E M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785593 232 26649
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 N918 L Q Q N P P E N K R S S W F F
Conservation
Percent
Protein Identity: 100 82.7 96.4 59.5 N.A. 57.7 38.3 N.A. N.A. 21.2 N.A. 45.3 N.A. N.A. N.A. N.A. 22.5
Protein Similarity: 100 84.3 97.9 63.9 N.A. 66 44.4 N.A. N.A. 34.3 N.A. 61.7 N.A. N.A. N.A. N.A. 39.2
P-Site Identity: 100 20 100 20 N.A. 0 6.6 N.A. N.A. 26.6 N.A. 20 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 33.3 100 40 N.A. 0 40 N.A. N.A. 40 N.A. 40 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 20.5
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 30
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 20
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 20 0 10 0 0 0 0 0 0 10 10 0 % A
% Cys: 0 10 0 10 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 20 10 20 20 10 10 0 10 40 0 20 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % F
% Gly: 0 0 0 0 0 0 0 0 0 30 0 0 20 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % I
% Lys: 0 0 20 0 0 0 0 10 10 0 10 0 10 0 0 % K
% Leu: 50 50 0 10 0 0 0 0 40 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % M
% Asn: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 50 30 0 0 0 0 0 0 0 20 0 % P
% Gln: 0 10 30 10 20 0 0 0 0 0 10 10 10 0 10 % Q
% Arg: 0 0 20 0 0 0 20 10 0 20 0 0 10 10 10 % R
% Ser: 10 10 0 0 0 10 20 30 0 0 50 10 0 0 0 % S
% Thr: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % T
% Val: 20 0 0 0 0 0 0 0 20 10 0 10 0 0 30 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _