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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPPDE1
All Species:
44.55
Human Site:
S157
Identified Species:
70
UniProt:
Q9BSY9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BSY9
NP_057160.2
194
21444
S157
L
T
P
A
A
L
Q
S
S
V
S
Q
E
L
Q
Chimpanzee
Pan troglodytes
XP_001137311
211
23531
S174
L
T
P
A
A
L
Q
S
S
V
S
Q
E
L
Q
Rhesus Macaque
Macaca mulatta
XP_001102905
352
37532
S315
L
T
P
A
A
L
Q
S
S
V
S
Q
E
L
Q
Dog
Lupus familis
XP_547498
145
15953
S108
L
T
P
A
A
L
Q
S
S
V
S
Q
E
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9D291
194
21416
S157
L
T
P
A
A
L
Q
S
S
V
S
Q
E
L
Q
Rat
Rattus norvegicus
Q5XIT6
194
21400
S157
L
T
P
A
A
L
Q
S
S
V
S
Q
E
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513647
263
28410
S219
L
T
P
A
A
L
Q
S
S
V
S
Q
E
L
Q
Chicken
Gallus gallus
Q5ZIV7
193
21391
S156
L
T
P
A
A
L
Q
S
S
V
S
Q
E
L
Q
Frog
Xenopus laevis
Q5PQ09
192
21397
S156
L
T
P
A
A
L
Q
S
S
I
S
Q
E
L
Q
Zebra Danio
Brachydanio rerio
Q6DC39
196
21840
S156
L
T
P
A
A
L
Q
S
S
V
S
Q
E
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610613
205
23309
S158
L
C
G
Q
E
I
P
S
W
V
N
R
L
A
H
Honey Bee
Apis mellifera
XP_623062
205
23265
S162
V
N
R
L
A
Y
F
S
S
C
V
P
F
L
Q
Nematode Worm
Caenorhab. elegans
NP_741592
315
34260
A163
L
T
P
I
V
L
Q
A
S
V
D
E
K
K
R
Sea Urchin
Strong. purpuratus
XP_794040
195
22027
R156
A
R
L
P
F
M
E
R
M
L
P
K
E
W
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93VG8
224
25331
N184
F
S
D
E
D
E
S
N
S
E
A
S
S
V
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.6
54.8
73.7
N.A.
96.9
96.3
N.A.
66.9
94.8
86.5
82.6
N.A.
53.6
56.5
37.7
53.3
Protein Similarity:
100
89
54.8
74.2
N.A.
98.9
97.9
N.A.
69.9
98.9
95.3
92.3
N.A.
73.6
73.1
50.7
71.7
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
20
33.3
46.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
40
40
73.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
67
74
0
0
7
0
0
7
0
0
7
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
7
0
7
0
0
0
0
0
7
0
0
0
0
% D
% Glu:
0
0
0
7
7
7
7
0
0
7
0
7
74
0
0
% E
% Phe:
7
0
0
0
7
0
7
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
0
7
0
7
0
0
0
7
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
7
7
7
0
% K
% Leu:
80
0
7
7
0
74
0
0
0
7
0
0
7
74
7
% L
% Met:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
7
0
0
7
0
0
0
0
% N
% Pro:
0
0
74
7
0
0
7
0
0
0
7
7
0
0
0
% P
% Gln:
0
0
0
7
0
0
74
0
0
0
0
67
0
0
74
% Q
% Arg:
0
7
7
0
0
0
0
7
0
0
0
7
0
0
7
% R
% Ser:
0
7
0
0
0
0
7
80
87
0
67
7
7
0
7
% S
% Thr:
0
74
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
7
0
0
0
7
0
0
0
0
74
7
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
7
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _