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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPPDE1
All Species:
41.82
Human Site:
T66
Identified Species:
65.71
UniProt:
Q9BSY9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BSY9
NP_057160.2
194
21444
T66
N
A
S
E
L
G
E
T
F
K
F
K
E
A
V
Chimpanzee
Pan troglodytes
XP_001137311
211
23531
T83
N
A
S
E
L
G
E
T
F
K
F
K
E
A
V
Rhesus Macaque
Macaca mulatta
XP_001102905
352
37532
T224
N
A
S
E
L
G
E
T
F
K
F
K
E
A
V
Dog
Lupus familis
XP_547498
145
15953
R22
S
G
I
E
V
Y
G
R
A
V
V
L
G
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D291
194
21416
T66
N
A
S
E
L
G
E
T
F
K
F
K
E
A
V
Rat
Rattus norvegicus
Q5XIT6
194
21400
T66
N
A
A
E
L
G
E
T
F
K
F
K
E
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513647
263
28410
T128
S
A
S
E
L
G
E
T
F
K
F
K
E
A
V
Chicken
Gallus gallus
Q5ZIV7
193
21391
T65
N
A
S
E
L
G
E
T
F
K
F
K
E
A
V
Frog
Xenopus laevis
Q5PQ09
192
21397
T65
D
S
T
E
L
G
D
T
F
K
F
K
E
A
I
Zebra Danio
Brachydanio rerio
Q6DC39
196
21840
T65
D
A
T
E
L
G
E
T
F
K
F
K
E
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610613
205
23309
V65
L
G
V
F
H
S
G
V
E
A
F
G
T
E
F
Honey Bee
Apis mellifera
XP_623062
205
23265
T65
S
G
V
E
I
Y
G
T
E
Y
A
Y
G
G
H
Nematode Worm
Caenorhab. elegans
NP_741592
315
34260
T72
D
A
E
E
L
G
E
T
F
K
F
K
E
S
I
Sea Urchin
Strong. purpuratus
XP_794040
195
22027
F66
P
F
P
F
T
G
I
F
E
I
E
P
R
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93VG8
224
25331
R87
N
C
P
G
F
I
F
R
R
S
V
L
L
G
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.6
54.8
73.7
N.A.
96.9
96.3
N.A.
66.9
94.8
86.5
82.6
N.A.
53.6
56.5
37.7
53.3
Protein Similarity:
100
89
54.8
74.2
N.A.
98.9
97.9
N.A.
69.9
98.9
95.3
92.3
N.A.
73.6
73.1
50.7
71.7
P-Site Identity:
100
100
100
6.6
N.A.
100
93.3
N.A.
93.3
100
66.6
80
N.A.
6.6
13.3
73.3
13.3
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
100
100
100
100
N.A.
6.6
26.6
93.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
7
0
0
0
0
0
7
7
7
0
0
60
0
% A
% Cys:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
0
0
0
7
0
0
0
0
0
0
7
0
% D
% Glu:
0
0
7
80
0
0
60
0
20
0
7
0
67
7
0
% E
% Phe:
0
7
0
14
7
0
7
7
67
0
74
0
0
0
7
% F
% Gly:
0
20
0
7
0
74
20
0
0
0
0
7
14
14
0
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
0
0
7
0
7
7
7
0
0
7
0
0
0
0
20
% I
% Lys:
0
0
0
0
0
0
0
0
0
67
0
67
0
0
0
% K
% Leu:
7
0
0
0
67
0
0
0
0
0
0
14
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
0
14
0
0
0
0
0
0
0
0
7
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
14
7
0
0
0
7
0
0
% R
% Ser:
20
7
40
0
0
7
0
0
0
7
0
0
0
14
0
% S
% Thr:
0
0
14
0
7
0
0
74
0
0
0
0
7
0
14
% T
% Val:
0
0
14
0
7
0
0
7
0
7
14
0
0
0
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
14
0
0
0
7
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _