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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FUZ
All Species:
13.94
Human Site:
S322
Identified Species:
43.81
UniProt:
Q9BT04
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BT04
NP_079405.2
418
45679
S322
P
L
G
D
K
E
P
S
P
E
Q
R
R
R
L
Chimpanzee
Pan troglodytes
XP_001173174
387
42334
I296
G
F
P
L
H
T
D
I
L
G
L
L
L
L
H
Rhesus Macaque
Macaca mulatta
XP_001113662
315
34619
R224
E
P
S
P
E
Q
R
R
R
L
L
R
N
F
Y
Dog
Lupus familis
XP_533613
419
45762
S322
P
S
G
D
Q
E
P
S
P
E
Q
R
R
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UYI6
415
45570
S322
P
S
K
D
K
E
P
S
P
E
Q
R
R
R
L
Rat
Rattus norvegicus
Q3B756
415
45388
S322
P
S
K
D
K
E
P
S
P
E
Q
R
R
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O16868
416
46243
S319
F
T
R
N
L
N
Q
S
A
S
V
K
R
I
I
Honey Bee
Apis mellifera
XP_625077
381
42800
S290
E
T
L
G
V
S
G
S
H
R
L
D
I
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89
73.6
89.9
N.A.
86.3
85.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
28.9
29.8
N.A.
N.A.
Protein Similarity:
100
89.9
74.1
93
N.A.
91.6
92.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
49.5
49
N.A.
N.A.
P-Site Identity:
100
0
6.6
86.6
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
0
20
93.3
N.A.
86.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
50
0
0
13
0
0
0
0
13
0
0
0
% D
% Glu:
25
0
0
0
13
50
0
0
0
50
0
0
0
0
0
% E
% Phe:
13
13
0
0
0
0
0
0
0
0
0
0
0
13
0
% F
% Gly:
13
0
25
13
0
0
13
0
0
13
0
0
0
0
0
% G
% His:
0
0
0
0
13
0
0
0
13
0
0
0
0
0
13
% H
% Ile:
0
0
0
0
0
0
0
13
0
0
0
0
13
13
13
% I
% Lys:
0
0
25
0
38
0
0
0
0
0
0
13
0
0
0
% K
% Leu:
0
13
13
13
13
0
0
0
13
13
38
13
13
25
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
13
0
13
0
0
0
0
0
0
13
0
0
% N
% Pro:
50
13
13
13
0
0
50
0
50
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
13
13
13
0
0
0
50
0
0
0
0
% Q
% Arg:
0
0
13
0
0
0
13
13
13
13
0
63
63
50
13
% R
% Ser:
0
38
13
0
0
13
0
75
0
13
0
0
0
0
0
% S
% Thr:
0
25
0
0
0
13
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
13
0
0
0
0
0
13
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _