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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FUZ All Species: 13.33
Human Site: Y220 Identified Species: 41.9
UniProt: Q9BT04 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BT04 NP_079405.2 418 45679 Y220 P P Q T A R D Y P V Y L P H G
Chimpanzee Pan troglodytes XP_001173174 387 42334 G210 V L L P W L V G S L P P Q T A
Rhesus Macaque Macaca mulatta XP_001113662 315 34619 L138 R L L T L T L L P S L E L C L
Dog Lupus familis XP_533613 419 45762 Y220 P P Q A A R D Y P V Y L P H G
Cat Felis silvestris
Mouse Mus musculus Q3UYI6 415 45570 Y220 P P Q A A R D Y P V Y L P H G
Rat Rattus norvegicus Q3B756 415 45388 Y220 P P Q A A R D Y P V Y L P H G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O16868 416 46243 P222 S T M Q H D V P V Y L P V K S
Honey Bee Apis mellifera XP_625077 381 42800 Y204 A I N T E D T Y T T R D I P V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89 73.6 89.9 N.A. 86.3 85.8 N.A. N.A. N.A. N.A. N.A. N.A. 28.9 29.8 N.A. N.A.
Protein Similarity: 100 89.9 74.1 93 N.A. 91.6 92.1 N.A. N.A. N.A. N.A. N.A. N.A. 49.5 49 N.A. N.A.
P-Site Identity: 100 0 13.3 93.3 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. N.A. N.A. 0 13.3 N.A. N.A.
P-Site Similarity: 100 6.6 13.3 93.3 N.A. 93.3 93.3 N.A. N.A. N.A. N.A. N.A. N.A. 0 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 38 50 0 0 0 0 0 0 0 0 0 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % C
% Asp: 0 0 0 0 0 25 50 0 0 0 0 13 0 0 0 % D
% Glu: 0 0 0 0 13 0 0 0 0 0 0 13 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 50 % G
% His: 0 0 0 0 13 0 0 0 0 0 0 0 0 50 0 % H
% Ile: 0 13 0 0 0 0 0 0 0 0 0 0 13 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % K
% Leu: 0 25 25 0 13 13 13 13 0 13 25 50 13 0 13 % L
% Met: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 50 50 0 13 0 0 0 13 63 0 13 25 50 13 0 % P
% Gln: 0 0 50 13 0 0 0 0 0 0 0 0 13 0 0 % Q
% Arg: 13 0 0 0 0 50 0 0 0 0 13 0 0 0 0 % R
% Ser: 13 0 0 0 0 0 0 0 13 13 0 0 0 0 13 % S
% Thr: 0 13 0 38 0 13 13 0 13 13 0 0 0 13 0 % T
% Val: 13 0 0 0 0 0 25 0 13 50 0 0 13 0 13 % V
% Trp: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 63 0 13 50 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _