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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALG1 All Species: 8.79
Human Site: S239 Identified Species: 13.81
UniProt: Q9BT22 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BT22 NP_061982.3 464 52518 S239 R L F M K L G S M H S P F R A
Chimpanzee Pan troglodytes XP_510796 464 52562 S239 R L F M K L G S T H S P F R A
Rhesus Macaque Macaca mulatta XP_001099380 456 51984 G231 W L F M K L G G T Y S P F R A
Dog Lupus familis XP_851486 464 52294 C239 Q L F M K L G C T Y P A F K A
Cat Felis silvestris
Mouse Mus musculus Q921Q3 482 54399 H239 E L F M K L S H T Y S P F Q S
Rat Rattus norvegicus NP_001101734 303 34263 F109 Q Y G V K V V F Q A V Y L L W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414707 511 57427 K285 Q L Y L K L A K D Y E P F K P
Frog Xenopus laevis NP_001091244 485 55591 K257 K L F M N L A K E Y P P F R Y
Zebra Danio Brachydanio rerio NP_956161 488 55045 S261 E L F V R M G S A Y L P F R P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650662 446 50953 K217 E L Y L K L A K D Y P Q F Q A
Honey Bee Apis mellifera XP_623777 444 52239 C237 N S T I F T E C I K N E I K L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792199 410 46108 S211 T A F T S M A S G E A R R L D
Poplar Tree Populus trichocarpa XP_002330745 481 54079 E243 M G S P N L N E T L F T T M V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_173105 465 52302 L232 Y D F I S R E L E N Q E L N E
Baker's Yeast Sacchar. cerevisiae P16661 449 51911 P228 C A V L Y D R P A S Q F Q P L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 90.9 81.6 N.A. 77.3 52.1 N.A. N.A. 59.8 60.4 58.6 N.A. 44.4 43.5 N.A. 52.8
Protein Similarity: 100 99.3 93.3 88.3 N.A. 84.4 57.3 N.A. N.A. 71.6 74 73.7 N.A. 61.6 61.2 N.A. 66.5
P-Site Identity: 100 93.3 73.3 53.3 N.A. 53.3 6.6 N.A. N.A. 33.3 46.6 46.6 N.A. 33.3 0 N.A. 13.3
P-Site Similarity: 100 93.3 80 73.3 N.A. 73.3 26.6 N.A. N.A. 66.6 60 73.3 N.A. 60 26.6 N.A. 26.6
Percent
Protein Identity: 42.8 N.A. N.A. 43.4 35.1 N.A.
Protein Similarity: 58.2 N.A. N.A. 61 54 N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 0 N.A.
P-Site Similarity: 6.6 N.A. N.A. 20 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 14 0 0 0 0 27 0 14 7 7 7 0 0 34 % A
% Cys: 7 0 0 0 0 0 0 14 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 7 0 0 14 0 0 0 0 0 7 % D
% Glu: 20 0 0 0 0 0 14 7 14 7 7 14 0 0 7 % E
% Phe: 0 0 60 0 7 0 0 7 0 0 7 7 60 0 0 % F
% Gly: 0 7 7 0 0 0 34 7 7 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 7 0 14 0 0 0 0 0 % H
% Ile: 0 0 0 14 0 0 0 0 7 0 0 0 7 0 0 % I
% Lys: 7 0 0 0 54 0 0 20 0 7 0 0 0 20 0 % K
% Leu: 0 60 0 20 0 60 0 7 0 7 7 0 14 14 14 % L
% Met: 7 0 0 40 0 14 0 0 7 0 0 0 0 7 0 % M
% Asn: 7 0 0 0 14 0 7 0 0 7 7 0 0 7 0 % N
% Pro: 0 0 0 7 0 0 0 7 0 0 20 47 0 7 14 % P
% Gln: 20 0 0 0 0 0 0 0 7 0 14 7 7 14 0 % Q
% Arg: 14 0 0 0 7 7 7 0 0 0 0 7 7 34 0 % R
% Ser: 0 7 7 0 14 0 7 27 0 7 27 0 0 0 7 % S
% Thr: 7 0 7 7 0 7 0 0 34 0 0 7 7 0 0 % T
% Val: 0 0 7 14 0 7 7 0 0 0 7 0 0 0 7 % V
% Trp: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 7 7 14 0 7 0 0 0 0 47 0 7 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _