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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALG1 All Species: 28.48
Human Site: Y126 Identified Species: 44.76
UniProt: Q9BT22 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BT22 NP_061982.3 464 52518 Y126 M W R E P G A Y I F L Q N P P
Chimpanzee Pan troglodytes XP_510796 464 52562 Y126 M W R E P G A Y I F L Q N P P
Rhesus Macaque Macaca mulatta XP_001099380 456 51984 Y118 M W R E P G D Y I F L Q N P P
Dog Lupus familis XP_851486 464 52294 Y126 I C R E P A A Y I F L Q N P P
Cat Felis silvestris
Mouse Mus musculus Q921Q3 482 54399 Y126 M R M D P A A Y I F L Q N P P
Rat Rattus norvegicus NP_001101734 303 34263
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414707 511 57427 Y172 L R M D P P S Y V L L Q N P P
Frog Xenopus laevis NP_001091244 485 55591 Y144 L K I D P L S Y I I L Q N P P
Zebra Danio Brachydanio rerio NP_956161 488 55045 Y148 M T I E D Q G Y I L M Q N P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650662 446 50953 F101 I S I G R P S F L L V Q N P P
Honey Bee Apis mellifera XP_623777 444 52239 Y106 F T K K L S N Y I L V Q N P P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792199 410 46108 V103 V Y G S K F V V D M H N Y G Y
Poplar Tree Populus trichocarpa XP_002330745 481 54079 V104 V K I P P P D V F L V Q N P P
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_173105 465 52302 I103 V K V P A P D I F L V Q N P P
Baker's Yeast Sacchar. cerevisiae P16661 449 51911 F108 G G G T S V I F M V K K V L F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 90.9 81.6 N.A. 77.3 52.1 N.A. N.A. 59.8 60.4 58.6 N.A. 44.4 43.5 N.A. 52.8
Protein Similarity: 100 99.3 93.3 88.3 N.A. 84.4 57.3 N.A. N.A. 71.6 74 73.7 N.A. 61.6 61.2 N.A. 66.5
P-Site Identity: 100 100 93.3 80 N.A. 73.3 0 N.A. N.A. 46.6 53.3 53.3 N.A. 26.6 40 N.A. 0
P-Site Similarity: 100 100 93.3 86.6 N.A. 80 0 N.A. N.A. 73.3 73.3 60 N.A. 60 60 N.A. 13.3
Percent
Protein Identity: 42.8 N.A. N.A. 43.4 35.1 N.A.
Protein Similarity: 58.2 N.A. N.A. 61 54 N.A.
P-Site Identity: 33.3 N.A. N.A. 26.6 0 N.A.
P-Site Similarity: 46.6 N.A. N.A. 40 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 14 27 0 0 0 0 0 0 0 0 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 20 7 0 20 0 7 0 0 0 0 0 0 % D
% Glu: 0 0 0 34 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 7 0 0 0 0 7 0 14 14 34 0 0 0 0 7 % F
% Gly: 7 7 14 7 0 20 7 0 0 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % H
% Ile: 14 0 27 0 0 0 7 7 54 7 0 0 0 0 0 % I
% Lys: 0 20 7 7 7 0 0 0 0 0 7 7 0 0 0 % K
% Leu: 14 0 0 0 7 7 0 0 7 40 47 0 0 7 0 % L
% Met: 34 0 14 0 0 0 0 0 7 7 7 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 0 7 80 0 0 % N
% Pro: 0 0 0 14 54 27 0 0 0 0 0 0 0 80 80 % P
% Gln: 0 0 0 0 0 7 0 0 0 0 0 80 0 0 0 % Q
% Arg: 0 14 27 0 7 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 7 0 7 7 7 20 0 0 0 0 0 0 0 0 % S
% Thr: 0 14 0 7 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 20 0 7 0 0 7 7 14 7 7 27 0 7 0 0 % V
% Trp: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 60 0 0 0 0 7 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _