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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INPP5K All Species: 24.24
Human Site: T118 Identified Species: 59.26
UniProt: Q9BT40 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BT40 NP_001129114.1 448 51090 T118 Q I L S T K S T P T G L F G Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001117306 555 61812 T225 Q I L S T K S T P T G L F G Y
Dog Lupus familis XP_537766 624 69422 T293 Q I L S T K S T P T G L F G Y
Cat Felis silvestris
Mouse Mus musculus Q8C5L6 468 54140 T136 Q I I S T K S T P T G L Y G Y
Rat Rattus norvegicus Q9JMC1 1001 107190 T524 R D V Q T D C T R T G L G G Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507443 768 84124 T271 Q N V Q T D C T R T G L G G Y
Chicken Gallus gallus XP_001234813 858 98308 T505 R D V R T N Y T R T G L Y G Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573135 508 58954 T146 Q D I E A E F T R T G F G G I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34370 398 45188 I118 L T G H K G S I G V R L Q L A
Sea Urchin Strong. purpuratus XP_780987 442 50512 I125 G N K G A V T I R F D C Y G R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 77.8 57.5 N.A. 72.6 23.7 N.A. 29.5 31.1 N.A. N.A. N.A. 30.1 N.A. 21.8 35
Protein Similarity: 100 N.A. 78.7 62.6 N.A. 82.4 31.3 N.A. 39.4 40.3 N.A. N.A. N.A. 49.2 N.A. 40.8 54.4
P-Site Identity: 100 N.A. 100 100 N.A. 86.6 46.6 N.A. 53.3 46.6 N.A. N.A. N.A. 33.3 N.A. 13.3 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 60 N.A. 60 66.6 N.A. N.A. N.A. 46.6 N.A. 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 20 0 0 0 0 10 0 0 0 % C
% Asp: 0 30 0 0 0 20 0 0 0 0 10 0 0 0 0 % D
% Glu: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 10 0 10 30 0 0 % F
% Gly: 10 0 10 10 0 10 0 0 10 0 80 0 30 90 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 40 20 0 0 0 0 20 0 0 0 0 0 0 10 % I
% Lys: 0 0 10 0 10 40 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 30 0 0 0 0 0 0 0 0 80 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 20 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 40 0 0 0 0 0 0 % P
% Gln: 60 0 0 20 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 20 0 0 10 0 0 0 0 50 0 10 0 0 0 10 % R
% Ser: 0 0 0 40 0 0 50 0 0 0 0 0 0 0 0 % S
% Thr: 0 10 0 0 70 0 10 80 0 80 0 0 0 0 0 % T
% Val: 0 0 30 0 0 10 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 30 0 70 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _