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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS4
All Species:
47.27
Human Site:
S178
Identified Species:
61.18
UniProt:
Q9BT78
Number Species:
17
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BT78
NP_057213.2
406
46269
S178
A
S
L
L
Q
N
E
S
T
N
E
Q
L
Q
I
Chimpanzee
Pan troglodytes
XP_001136883
398
45560
S170
A
S
L
L
Q
N
E
S
T
N
E
Q
L
Q
I
Rhesus Macaque
Macaca mulatta
XP_001082657
355
40767
R148
A
R
V
L
D
Y
R
R
K
F
I
E
A
A
Q
Dog
Lupus familis
XP_859288
395
45114
S167
A
S
L
L
Q
N
E
S
T
N
E
Q
L
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
O88544
406
46266
S178
A
S
L
L
Q
N
E
S
T
N
E
Q
L
Q
I
Rat
Rattus norvegicus
Q68FS2
406
46271
S178
A
S
L
L
Q
N
E
S
T
N
E
Q
L
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507527
188
21373
Chicken
Gallus gallus
NP_001006447
411
46767
S183
A
S
L
L
Q
N
E
S
T
N
E
Q
L
Q
I
Frog
Xenopus laevis
NP_001091298
406
46331
S178
A
S
L
L
Q
N
E
S
T
N
E
K
L
Q
I
Zebra Danio
Brachydanio rerio
Q6P0H6
406
46327
S178
A
S
L
L
Q
N
E
S
T
N
E
Q
L
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V345
407
46455
T185
A
S
L
L
Q
A
E
T
N
S
E
E
L
Q
V
Honey Bee
Apis mellifera
XP_623684
418
48124
S181
A
S
L
L
Q
A
E
S
K
N
E
Q
L
Q
I
Nematode Worm
Caenorhab. elegans
Q9N359
412
46114
G191
S
I
L
M
V
D
L
G
A
N
P
D
I
Q
I
Sea Urchin
Strong. purpuratus
XP_791860
354
40869
K147
Y
A
R
M
L
D
Y
K
R
K
F
I
E
A
A
Poplar Tree
Populus trichocarpa
XP_002320585
397
45327
S170
A
S
F
L
V
S
N
S
Q
H
E
V
L
N
L
Maize
Zea mays
NP_001131365
399
45155
S172
A
S
F
L
V
T
N
S
H
Q
E
V
L
N
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L5U0
397
44939
S170
A
S
F
L
V
S
N
S
Q
N
E
V
L
N
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S0P8
440
47908
D197
N
I
I
H
N
V
A
D
D
N
P
V
L
N
L
Conservation
Percent
Protein Identity:
100
95.3
87.4
97
N.A.
99.5
99
N.A.
45
97.8
95.5
94.5
N.A.
70.5
76.5
35.1
68.7
Protein Similarity:
100
96
87.4
97.2
N.A.
99.7
99.5
N.A.
46
98.7
98
97.5
N.A.
82.5
85.1
56
77
P-Site Identity:
100
100
13.3
100
N.A.
100
100
N.A.
0
100
93.3
100
N.A.
60
86.6
26.6
0
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
0
100
100
100
N.A.
86.6
86.6
53.3
20
Percent
Protein Identity:
49
48.5
N.A.
48.7
N.A.
35.9
Protein Similarity:
67.4
64.7
N.A.
66
N.A.
56.5
P-Site Identity:
40
40
N.A.
46.6
N.A.
13.3
P-Site Similarity:
60
46.6
N.A.
60
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
78
6
0
0
0
12
6
0
6
0
0
0
6
12
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
6
12
0
6
6
0
0
6
0
0
0
% D
% Glu:
0
0
0
0
0
0
56
0
0
0
73
12
6
0
0
% E
% Phe:
0
0
17
0
0
0
0
0
0
6
6
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% G
% His:
0
0
0
6
0
0
0
0
6
6
0
0
0
0
0
% H
% Ile:
0
12
6
0
0
0
0
0
0
0
6
6
6
0
56
% I
% Lys:
0
0
0
0
0
0
0
6
12
6
0
6
0
0
0
% K
% Leu:
0
0
62
78
6
0
6
0
0
0
0
0
78
0
23
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
0
0
6
45
17
0
6
67
0
0
0
23
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% P
% Gln:
0
0
0
0
56
0
0
0
12
6
0
45
0
62
6
% Q
% Arg:
0
6
6
0
0
0
6
6
6
0
0
0
0
0
0
% R
% Ser:
6
73
0
0
0
12
0
67
0
6
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
6
0
6
45
0
0
0
0
0
0
% T
% Val:
0
0
6
0
23
6
0
0
0
0
0
23
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
6
6
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _