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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS4
All Species:
33.94
Human Site:
S220
Identified Species:
43.92
UniProt:
Q9BT78
Number Species:
17
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BT78
NP_057213.2
406
46269
S220
Y
K
T
I
V
H
E
S
E
R
L
E
A
L
K
Chimpanzee
Pan troglodytes
XP_001136883
398
45560
S212
Y
K
T
I
V
H
E
S
E
R
L
E
A
L
K
Rhesus Macaque
Macaca mulatta
XP_001082657
355
40767
Q190
I
L
A
S
A
G
Q
Q
R
S
R
M
L
A
T
Dog
Lupus familis
XP_859288
395
45114
S209
Y
K
T
I
V
H
E
S
E
R
L
E
A
L
K
Cat
Felis silvestris
Mouse
Mus musculus
O88544
406
46266
S220
Y
K
T
I
V
H
E
S
E
R
L
E
A
L
K
Rat
Rattus norvegicus
Q68FS2
406
46271
S220
Y
K
T
I
V
H
E
S
E
R
L
E
A
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507527
188
21373
A23
S
G
S
H
K
D
L
A
G
K
Y
R
Q
I
L
Chicken
Gallus gallus
NP_001006447
411
46767
S225
Y
K
S
I
V
H
E
S
E
R
L
E
A
L
K
Frog
Xenopus laevis
NP_001091298
406
46331
T220
Y
K
T
I
V
H
E
T
E
R
M
E
A
L
K
Zebra Danio
Brachydanio rerio
Q6P0H6
406
46327
T220
Y
K
S
I
V
H
E
T
E
R
L
E
A
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V345
407
46455
G227
Y
R
K
I
V
D
Q
G
E
R
M
T
A
L
K
Honey Bee
Apis mellifera
XP_623684
418
48124
D223
Y
R
S
I
I
H
E
D
E
R
M
T
A
L
R
Nematode Worm
Caenorhab. elegans
Q9N359
412
46114
S233
A
T
E
Q
L
P
N
S
D
K
L
T
A
L
G
Sea Urchin
Strong. purpuratus
XP_791860
354
40869
Q189
T
I
L
A
S
A
G
Q
Q
R
S
R
M
L
A
Poplar Tree
Populus trichocarpa
XP_002320585
397
45327
E212
Q
I
E
K
R
Q
I
E
D
E
T
I
D
E
E
Maize
Zea mays
NP_001131365
399
45155
G214
Q
I
E
Q
R
K
I
G
D
E
E
I
D
E
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L5U0
397
44939
G212
Q
I
E
Q
R
Q
I
G
D
E
E
I
D
E
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S0P8
440
47908
E239
L
S
P
A
I
A
E
E
E
R
L
H
T
L
S
Conservation
Percent
Protein Identity:
100
95.3
87.4
97
N.A.
99.5
99
N.A.
45
97.8
95.5
94.5
N.A.
70.5
76.5
35.1
68.7
Protein Similarity:
100
96
87.4
97.2
N.A.
99.7
99.5
N.A.
46
98.7
98
97.5
N.A.
82.5
85.1
56
77
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
0
93.3
86.6
86.6
N.A.
53.3
53.3
26.6
13.3
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
26.6
100
100
100
N.A.
73.3
86.6
46.6
20
Percent
Protein Identity:
49
48.5
N.A.
48.7
N.A.
35.9
Protein Similarity:
67.4
64.7
N.A.
66
N.A.
56.5
P-Site Identity:
0
0
N.A.
0
N.A.
33.3
P-Site Similarity:
13.3
6.6
N.A.
6.6
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
6
12
6
12
0
6
0
0
0
0
62
6
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
12
0
6
23
0
0
0
17
0
0
% D
% Glu:
0
0
23
0
0
0
56
12
62
17
12
45
0
17
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
6
0
0
0
6
6
17
6
0
0
0
0
0
6
% G
% His:
0
0
0
6
0
50
0
0
0
0
0
6
0
0
0
% H
% Ile:
6
23
0
56
12
0
17
0
0
0
0
17
0
6
0
% I
% Lys:
0
45
6
6
6
6
0
0
0
12
0
0
0
0
50
% K
% Leu:
6
6
6
0
6
0
6
0
0
0
50
0
6
73
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
17
6
6
0
0
% M
% Asn:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
12
% N
% Pro:
0
0
6
0
0
6
0
0
0
0
0
0
0
0
0
% P
% Gln:
17
0
0
17
0
12
12
12
6
0
0
0
6
0
0
% Q
% Arg:
0
12
0
0
17
0
0
0
6
67
6
12
0
0
6
% R
% Ser:
6
6
23
6
6
0
0
39
0
6
6
0
0
0
6
% S
% Thr:
6
6
34
0
0
0
0
12
0
0
6
17
6
0
6
% T
% Val:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
56
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _