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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS4
All Species:
31.82
Human Site:
S389
Identified Species:
41.18
UniProt:
Q9BT78
Number Species:
17
Phosphosite Substitution
Charge Score:
0.12
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BT78
NP_057213.2
406
46269
S389
N
N
L
L
E
K
I
S
Q
T
A
P
E
W
T
Chimpanzee
Pan troglodytes
XP_001136883
398
45560
S381
N
N
L
L
E
K
I
S
Q
T
A
P
E
W
T
Rhesus Macaque
Macaca mulatta
XP_001082657
355
40767
A341
L
E
K
I
S
Q
T
A
P
E
W
T
A
Q
A
Dog
Lupus familis
XP_859288
395
45114
S378
N
N
L
L
E
K
I
S
Q
T
A
P
E
W
T
Cat
Felis silvestris
Mouse
Mus musculus
O88544
406
46266
S389
N
N
L
L
E
K
I
S
Q
T
A
P
E
W
T
Rat
Rattus norvegicus
Q68FS2
406
46271
S389
N
N
L
L
E
K
I
S
Q
T
A
P
E
W
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507527
188
21373
L174
Y
I
N
R
A
S
L
L
Q
N
E
S
T
N
E
Chicken
Gallus gallus
NP_001006447
411
46767
S394
N
N
L
L
E
K
I
S
Q
T
A
P
E
W
T
Frog
Xenopus laevis
NP_001091298
406
46331
S389
N
N
L
L
E
K
I
S
Q
T
A
P
D
W
T
Zebra Danio
Brachydanio rerio
Q6P0H6
406
46327
S389
N
N
L
L
E
K
I
S
Q
T
A
P
E
W
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V345
407
46455
E393
Y
Q
V
N
S
I
I
E
K
I
S
V
A
E
P
Honey Bee
Apis mellifera
XP_623684
418
48124
A394
N
Q
I
I
E
K
I
A
Q
T
E
P
E
W
I
Nematode Worm
Caenorhab. elegans
Q9N359
412
46114
N394
L
S
T
L
E
Q
I
N
K
V
S
D
M
I
V
Sea Urchin
Strong. purpuratus
XP_791860
354
40869
A340
I
I
E
K
I
V
G
A
V
P
E
W
A
A
S
Poplar Tree
Populus trichocarpa
XP_002320585
397
45327
N382
V
G
L
C
Q
A
L
N
D
V
L
D
S
M
A
Maize
Zea mays
NP_001131365
399
45155
N384
A
G
L
C
Q
A
L
N
D
I
L
D
S
M
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L5U0
397
44939
N382
S
G
L
C
Q
A
L
N
D
I
L
D
G
M
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S0P8
440
47908
E419
Q
A
L
A
E
D
L
E
R
I
T
D
D
L
L
Conservation
Percent
Protein Identity:
100
95.3
87.4
97
N.A.
99.5
99
N.A.
45
97.8
95.5
94.5
N.A.
70.5
76.5
35.1
68.7
Protein Similarity:
100
96
87.4
97.2
N.A.
99.7
99.5
N.A.
46
98.7
98
97.5
N.A.
82.5
85.1
56
77
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
6.6
100
93.3
100
N.A.
6.6
60
20
0
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
26.6
80
53.3
13.3
Percent
Protein Identity:
49
48.5
N.A.
48.7
N.A.
35.9
Protein Similarity:
67.4
64.7
N.A.
66
N.A.
56.5
P-Site Identity:
6.6
6.6
N.A.
6.6
N.A.
13.3
P-Site Similarity:
26.6
33.3
N.A.
33.3
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
0
6
6
17
0
17
0
0
45
0
17
6
17
% A
% Cys:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
6
0
0
17
0
0
28
12
0
0
% D
% Glu:
0
6
6
0
62
0
0
12
0
6
17
0
45
6
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
17
0
0
0
0
6
0
0
0
0
0
6
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
12
6
12
6
6
62
0
0
23
0
0
0
6
6
% I
% Lys:
0
0
6
6
0
50
0
0
12
0
0
0
0
0
0
% K
% Leu:
12
0
67
50
0
0
28
6
0
0
17
0
0
6
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
6
17
0
% M
% Asn:
50
45
6
6
0
0
0
23
0
6
0
0
0
6
0
% N
% Pro:
0
0
0
0
0
0
0
0
6
6
0
50
0
0
6
% P
% Gln:
6
12
0
0
17
12
0
0
56
0
0
0
0
6
0
% Q
% Arg:
0
0
0
6
0
0
0
0
6
0
0
0
0
0
0
% R
% Ser:
6
6
0
0
12
6
0
45
0
0
12
6
12
0
12
% S
% Thr:
0
0
6
0
0
0
6
0
0
50
6
6
6
0
45
% T
% Val:
6
0
6
0
0
6
0
0
6
12
0
6
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
6
6
0
50
0
% W
% Tyr:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _