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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS4
All Species:
19.09
Human Site:
S79
Identified Species:
24.71
UniProt:
Q9BT78
Number Species:
17
Phosphosite Substitution
Charge Score:
0.47
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BT78
NP_057213.2
406
46269
S79
H
L
P
N
L
P
D
S
T
A
K
E
I
Y
H
Chimpanzee
Pan troglodytes
XP_001136883
398
45560
S71
H
L
P
N
L
P
D
S
T
A
K
E
I
Y
H
Rhesus Macaque
Macaca mulatta
XP_001082657
355
40767
S54
S
F
E
E
Q
V
A
S
I
R
Q
H
L
A
S
Dog
Lupus familis
XP_859288
395
45114
L73
L
T
D
F
C
T
H
L
P
N
L
P
D
S
T
Cat
Felis silvestris
Mouse
Mus musculus
O88544
406
46266
S79
H
L
P
N
L
P
D
S
T
A
K
E
V
Y
H
Rat
Rattus norvegicus
Q68FS2
406
46271
S79
H
L
P
N
L
P
D
S
T
A
K
E
V
Y
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507527
188
21373
Chicken
Gallus gallus
NP_001006447
411
46767
S84
H
L
P
S
L
P
D
S
T
A
K
E
I
Y
H
Frog
Xenopus laevis
NP_001091298
406
46331
G79
L
L
P
S
L
P
D
G
I
A
K
E
I
Y
H
Zebra Danio
Brachydanio rerio
Q6P0H6
406
46327
D79
H
L
P
N
L
P
D
D
I
A
K
V
V
C
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V345
407
46455
D86
E
L
S
K
L
P
D
D
L
S
K
M
L
S
H
Honey Bee
Apis mellifera
XP_623684
418
48124
E82
R
L
L
L
L
P
D
E
V
S
M
A
I
S
H
Nematode Worm
Caenorhab. elegans
Q9N359
412
46114
E86
D
N
Q
H
L
E
S
E
C
V
K
A
I
S
E
Sea Urchin
Strong. purpuratus
XP_791860
354
40869
G53
V
S
F
E
E
Q
M
G
S
V
R
Q
H
L
S
Poplar Tree
Populus trichocarpa
XP_002320585
397
45327
E71
E
L
G
R
L
E
P
E
T
Q
K
E
I
A
H
Maize
Zea mays
NP_001131365
399
45155
D73
D
L
G
K
L
E
S
D
A
Q
K
E
V
A
H
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L5U0
397
44939
E71
E
L
G
R
L
E
P
E
T
Q
K
E
I
A
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S0P8
440
47908
D96
T
T
S
S
I
W
L
D
V
G
K
A
I
Q
Q
Conservation
Percent
Protein Identity:
100
95.3
87.4
97
N.A.
99.5
99
N.A.
45
97.8
95.5
94.5
N.A.
70.5
76.5
35.1
68.7
Protein Similarity:
100
96
87.4
97.2
N.A.
99.7
99.5
N.A.
46
98.7
98
97.5
N.A.
82.5
85.1
56
77
P-Site Identity:
100
100
6.6
0
N.A.
93.3
93.3
N.A.
0
93.3
73.3
66.6
N.A.
40
40
20
0
P-Site Similarity:
100
100
20
0
N.A.
100
100
N.A.
0
100
80
73.3
N.A.
53.3
46.6
26.6
20
Percent
Protein Identity:
49
48.5
N.A.
48.7
N.A.
35.9
Protein Similarity:
67.4
64.7
N.A.
66
N.A.
56.5
P-Site Identity:
46.6
33.3
N.A.
40
N.A.
13.3
P-Site Similarity:
46.6
40
N.A.
40
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
6
0
6
39
0
17
0
23
0
% A
% Cys:
0
0
0
0
6
0
0
0
6
0
0
0
0
6
0
% C
% Asp:
12
0
6
0
0
0
50
23
0
0
0
0
6
0
0
% D
% Glu:
17
0
6
12
6
23
0
23
0
0
0
50
0
0
6
% E
% Phe:
0
6
6
6
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
17
0
0
0
0
12
0
6
0
0
0
0
0
% G
% His:
34
0
0
6
0
0
6
0
0
0
0
6
6
0
62
% H
% Ile:
0
0
0
0
6
0
0
0
17
0
0
0
50
0
0
% I
% Lys:
0
0
0
12
0
0
0
0
0
0
73
0
0
0
0
% K
% Leu:
12
67
6
6
73
0
6
6
6
0
6
0
12
6
0
% L
% Met:
0
0
0
0
0
0
6
0
0
0
6
6
0
0
0
% M
% Asn:
0
6
0
28
0
0
0
0
0
6
0
0
0
0
0
% N
% Pro:
0
0
39
0
0
50
12
0
6
0
0
6
0
0
0
% P
% Gln:
0
0
6
0
6
6
0
0
0
17
6
6
0
6
12
% Q
% Arg:
6
0
0
12
0
0
0
0
0
6
6
0
0
0
0
% R
% Ser:
6
6
12
17
0
0
12
34
6
12
0
0
0
23
12
% S
% Thr:
6
12
0
0
0
6
0
0
39
0
0
0
0
0
6
% T
% Val:
6
0
0
0
0
6
0
0
12
12
0
6
23
0
0
% V
% Trp:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
34
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _