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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS4
All Species:
43.33
Human Site:
T344
Identified Species:
56.08
UniProt:
Q9BT78
Number Species:
17
Phosphosite Substitution
Charge Score:
0.12
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BT78
NP_057213.2
406
46269
T344
K
I
A
S
Q
M
I
T
E
G
R
M
N
G
F
Chimpanzee
Pan troglodytes
XP_001136883
398
45560
T336
K
I
A
S
Q
M
I
T
E
G
R
M
N
G
F
Rhesus Macaque
Macaca mulatta
XP_001082657
355
40767
F300
T
E
G
R
M
N
G
F
I
D
Q
I
D
G
I
Dog
Lupus familis
XP_859288
395
45114
T333
K
I
A
S
Q
M
I
T
E
G
R
M
N
G
F
Cat
Felis silvestris
Mouse
Mus musculus
O88544
406
46266
T344
K
I
A
S
Q
M
I
T
E
G
R
M
N
G
F
Rat
Rattus norvegicus
Q68FS2
406
46271
T344
K
I
A
S
Q
M
I
T
E
G
R
M
N
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507527
188
21373
E133
V
L
V
G
I
P
L
E
T
G
Q
K
Q
Y
N
Chicken
Gallus gallus
NP_001006447
411
46767
T349
K
I
A
S
Q
M
I
T
E
G
R
M
N
G
F
Frog
Xenopus laevis
NP_001091298
406
46331
T344
K
I
A
S
Q
M
I
T
E
G
R
M
N
G
F
Zebra Danio
Brachydanio rerio
Q6P0H6
406
46327
T344
K
I
A
S
Q
M
I
T
E
G
R
M
N
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V345
407
46455
T351
K
I
A
S
Q
M
I
T
E
G
R
M
N
G
H
Honey Bee
Apis mellifera
XP_623684
418
48124
T349
K
I
A
S
Q
M
I
T
E
G
R
M
N
G
Y
Nematode Worm
Caenorhab. elegans
Q9N359
412
46114
A351
T
E
A
A
E
S
M
A
G
E
M
I
S
S
E
Sea Urchin
Strong. purpuratus
XP_791860
354
40869
G299
I
S
E
G
R
M
N
G
Y
I
D
Q
I
D
S
Poplar Tree
Populus trichocarpa
XP_002320585
397
45327
S339
H
K
A
E
K
I
A
S
R
M
I
Y
E
D
R
Maize
Zea mays
NP_001131365
399
45155
S341
R
K
A
E
K
I
A
S
R
M
I
Y
E
D
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L5U0
397
44939
A339
R
K
A
E
K
I
A
A
N
M
I
G
Q
D
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S0P8
440
47908
E364
E
I
T
A
R
M
I
E
Q
G
R
L
A
G
S
Conservation
Percent
Protein Identity:
100
95.3
87.4
97
N.A.
99.5
99
N.A.
45
97.8
95.5
94.5
N.A.
70.5
76.5
35.1
68.7
Protein Similarity:
100
96
87.4
97.2
N.A.
99.7
99.5
N.A.
46
98.7
98
97.5
N.A.
82.5
85.1
56
77
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
6.6
100
100
100
N.A.
93.3
93.3
6.6
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
26.6
100
100
100
N.A.
93.3
100
40
13.3
Percent
Protein Identity:
49
48.5
N.A.
48.7
N.A.
35.9
Protein Similarity:
67.4
64.7
N.A.
66
N.A.
56.5
P-Site Identity:
6.6
6.6
N.A.
6.6
N.A.
40
P-Site Similarity:
26.6
33.3
N.A.
26.6
N.A.
73.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
78
12
0
0
17
12
0
0
0
0
6
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
6
6
0
6
23
0
% D
% Glu:
6
12
6
17
6
0
0
12
56
6
0
0
12
0
6
% E
% Phe:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
45
% F
% Gly:
0
0
6
12
0
0
6
6
6
67
0
6
0
67
0
% G
% His:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% H
% Ile:
6
62
0
0
6
17
62
0
6
6
17
12
6
0
6
% I
% Lys:
56
17
0
0
17
0
0
0
0
0
0
6
0
0
0
% K
% Leu:
0
6
0
0
0
0
6
0
0
0
0
6
0
0
0
% L
% Met:
0
0
0
0
6
67
6
0
0
17
6
56
0
0
0
% M
% Asn:
0
0
0
0
0
6
6
0
6
0
0
0
56
0
6
% N
% Pro:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
56
0
0
0
6
0
12
6
12
0
0
% Q
% Arg:
12
0
0
6
12
0
0
0
12
0
62
0
0
0
17
% R
% Ser:
0
6
0
56
0
6
0
12
0
0
0
0
6
6
12
% S
% Thr:
12
0
6
0
0
0
0
56
6
0
0
0
0
0
0
% T
% Val:
6
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
6
0
0
12
0
6
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _