KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TCHP
All Species:
8.48
Human Site:
Y187
Identified Species:
20.74
UniProt:
Q9BT92
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BT92
NP_001137324.1
498
61072
Y187
A
E
Q
E
N
K
R
Y
E
N
E
Y
E
R
A
Chimpanzee
Pan troglodytes
XP_509357
609
73748
Y187
A
E
Q
E
N
K
R
Y
E
N
E
Y
E
R
A
Rhesus Macaque
Macaca mulatta
XP_001116838
271
33527
N110
E
E
L
R
L
S
M
N
L
H
E
R
R
I
R
Dog
Lupus familis
XP_534716
541
65191
S217
K
E
E
E
N
K
R
S
E
N
E
Y
E
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3TVW5
497
60624
L186
E
K
Q
E
N
K
R
L
E
N
Q
Y
A
A
A
Rat
Rattus norvegicus
Q9JHZ4
837
96055
H502
R
E
L
E
N
L
Q
H
T
V
E
E
L
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520626
560
67289
F249
E
K
E
E
N
R
R
F
E
N
E
Y
E
A
S
Chicken
Gallus gallus
Frog
Xenopus laevis
A0AUT1
499
61178
L188
E
D
M
E
K
K
R
L
E
N
E
Y
E
L
A
Zebra Danio
Brachydanio rerio
Q1RM03
499
62332
F188
T
Q
E
E
K
Q
R
F
E
N
E
Y
E
R
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780692
561
66383
A189
A
R
E
Q
E
R
L
A
E
E
A
M
E
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.7
52.8
78.3
N.A.
77.3
25.2
N.A.
56.7
N.A.
59.1
56.1
N.A.
N.A.
N.A.
N.A.
40.6
Protein Similarity:
100
81.2
53.6
86.3
N.A.
88.1
37.6
N.A.
73.3
N.A.
77.3
76.3
N.A.
N.A.
N.A.
N.A.
62
P-Site Identity:
100
100
13.3
80
N.A.
60
33.3
N.A.
53.3
N.A.
60
53.3
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
20
86.6
N.A.
73.3
53.3
N.A.
86.6
N.A.
66.6
80
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
0
0
0
0
0
10
0
0
10
0
10
20
60
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
40
50
40
80
10
0
0
0
80
10
80
10
70
0
10
% E
% Phe:
0
0
0
0
0
0
0
20
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
10
20
0
0
20
50
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
20
0
10
10
10
20
10
0
0
0
10
10
0
% L
% Met:
0
0
10
0
0
0
10
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
60
0
0
10
0
70
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
30
10
0
10
10
0
0
0
10
0
0
10
0
% Q
% Arg:
10
10
0
10
0
20
70
0
0
0
0
10
10
40
10
% R
% Ser:
0
0
0
0
0
10
0
10
0
0
0
0
0
10
10
% S
% Thr:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
20
0
0
0
70
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _