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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: THUMPD2 All Species: 9.39
Human Site: S431 Identified Species: 20.67
UniProt: Q9BTF0 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BTF0 NP_079540 473 53367 S431 A S T S F E A S N H K F L D R
Chimpanzee Pan troglodytes XP_515428 503 56424 S461 A S T S F E A S N H K F L D R
Rhesus Macaque Macaca mulatta XP_001110330 503 56427 R461 V S T S F E A R N H E F L D R
Dog Lupus familis XP_540159 502 55930 S460 V S S S S E A S N Q E G L D K
Cat Felis silvestris
Mouse Mus musculus Q9CZB3 498 54658 V431 P S Q R A S S V Q C L G R M R
Rat Rattus norvegicus NP_001156978 549 59176 L461 P S Q K A S S L Q S L G R P L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514044 343 37762 K302 T I L L E A A K E W P D A N Y
Chicken Gallus gallus XP_001233369 494 54003 E451 S S L G A G I E E P V L S C G
Frog Xenopus laevis NP_001086861 469 52022 N428 V N K D N I V N K T H W F D S
Zebra Danio Brachydanio rerio XP_691263 446 49508 T405 S N A H K E S T E T H K T L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194807 468 52831 C421 N H G G L K A C V Y L L Q R A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.6 89.8 78.6 N.A. 65.2 57.1 N.A. 43.3 51.4 42.4 32.3 N.A. N.A. N.A. N.A. 23.2
Protein Similarity: 100 93.8 92 84.8 N.A. 77.1 69 N.A. 52.6 65.7 58.7 53.2 N.A. N.A. N.A. N.A. 45.2
P-Site Identity: 100 100 80 53.3 N.A. 13.3 6.6 N.A. 6.6 6.6 6.6 6.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 86.6 73.3 N.A. 20 13.3 N.A. 13.3 13.3 26.6 33.3 N.A. N.A. N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 0 10 0 28 10 55 0 0 0 0 0 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 10 0 10 0 0 0 10 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 10 0 46 0 % D
% Glu: 0 0 0 0 10 46 0 10 28 0 19 0 0 0 0 % E
% Phe: 0 0 0 0 28 0 0 0 0 0 0 28 10 0 0 % F
% Gly: 0 0 10 19 0 10 0 0 0 0 0 28 0 0 10 % G
% His: 0 10 0 10 0 0 0 0 0 28 19 0 0 0 0 % H
% Ile: 0 10 0 0 0 10 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 10 10 10 0 10 10 0 19 10 0 0 10 % K
% Leu: 0 0 19 10 10 0 0 10 0 0 28 19 37 10 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 10 19 0 0 10 0 0 10 37 0 0 0 0 10 0 % N
% Pro: 19 0 0 0 0 0 0 0 0 10 10 0 0 10 0 % P
% Gln: 0 0 19 0 0 0 0 0 19 10 0 0 10 0 0 % Q
% Arg: 0 0 0 10 0 0 0 10 0 0 0 0 19 10 37 % R
% Ser: 19 64 10 37 10 19 28 28 0 10 0 0 10 0 10 % S
% Thr: 10 0 28 0 0 0 0 10 0 19 0 0 10 0 0 % T
% Val: 28 0 0 0 0 0 10 10 10 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _