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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THUMPD2
All Species:
26.36
Human Site:
T249
Identified Species:
58
UniProt:
Q9BTF0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTF0
NP_079540
473
53367
T249
A
S
R
A
Y
I
K
T
A
G
L
R
S
T
I
Chimpanzee
Pan troglodytes
XP_515428
503
56424
T279
A
S
R
A
Y
I
K
T
A
G
L
R
S
T
I
Rhesus Macaque
Macaca mulatta
XP_001110330
503
56427
T279
A
S
R
A
Y
I
K
T
A
G
L
R
S
T
I
Dog
Lupus familis
XP_540159
502
55930
T278
A
S
R
A
Y
I
K
T
A
G
L
R
S
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZB3
498
54658
T249
A
S
R
T
Y
I
Q
T
A
G
L
R
S
T
I
Rat
Rattus norvegicus
NP_001156978
549
59176
T279
A
S
R
T
Y
L
Q
T
A
G
L
R
S
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514044
343
37762
K129
G
S
T
S
V
I
T
K
K
L
K
M
E
Q
T
Chicken
Gallus gallus
XP_001233369
494
54003
T269
A
N
R
E
Y
I
K
T
A
G
L
R
S
T
V
Frog
Xenopus laevis
NP_001086861
469
52022
N251
A
S
R
D
Y
I
R
N
T
G
L
R
S
T
T
Zebra Danio
Brachydanio rerio
XP_691263
446
49508
H230
A
S
R
S
Y
M
K
H
N
G
L
R
S
T
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194807
468
52831
I244
R
N
I
T
H
F
G
I
T
T
L
K
S
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.6
89.8
78.6
N.A.
65.2
57.1
N.A.
43.3
51.4
42.4
32.3
N.A.
N.A.
N.A.
N.A.
23.2
Protein Similarity:
100
93.8
92
84.8
N.A.
77.1
69
N.A.
52.6
65.7
58.7
53.2
N.A.
N.A.
N.A.
N.A.
45.2
P-Site Identity:
100
100
100
100
N.A.
86.6
80
N.A.
13.3
80
66.6
73.3
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
20
93.3
73.3
86.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
82
0
0
37
0
0
0
0
64
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
10
0
0
82
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
73
0
10
0
0
0
0
0
0
73
% I
% Lys:
0
0
0
0
0
0
55
10
10
0
10
10
0
0
0
% K
% Leu:
0
0
0
0
0
10
0
0
0
10
91
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
19
0
0
0
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
19
0
0
0
0
0
0
10
0
% Q
% Arg:
10
0
82
0
0
0
10
0
0
0
0
82
0
0
0
% R
% Ser:
0
82
0
19
0
0
0
0
0
0
0
0
91
0
0
% S
% Thr:
0
0
10
28
0
0
10
64
19
10
0
0
0
91
19
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
82
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _