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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IER2
All Species:
12.12
Human Site:
S126
Identified Species:
33.33
UniProt:
Q9BTL4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTL4
NP_004898.2
223
24196
S126
S
R
K
R
R
S
S
S
L
S
D
G
G
D
A
Chimpanzee
Pan troglodytes
XP_520307
238
26159
H126
L
Q
Q
Q
L
H
Q
H
Q
H
P
A
P
R
G
Rhesus Macaque
Macaca mulatta
XP_001110964
223
24189
S126
S
R
K
R
R
S
S
S
L
S
D
G
G
D
A
Dog
Lupus familis
XP_542033
222
24268
S126
S
R
K
R
R
N
S
S
L
S
D
G
G
D
V
Cat
Felis silvestris
Mouse
Mus musculus
P17950
221
24485
D126
R
K
R
R
S
S
S
D
L
S
D
S
S
D
A
Rat
Rattus norvegicus
Q6P7D3
221
24578
D126
R
K
R
R
S
S
S
D
L
S
D
G
S
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509938
243
26112
S126
S
C
G
R
L
P
S
S
V
S
A
P
P
R
H
Chicken
Gallus gallus
Frog
Xenopus laevis
Q66IT9
293
31857
E126
H
S
P
H
P
A
K
E
P
Q
S
H
A
A
F
Zebra Danio
Brachydanio rerio
Q6NYT3
301
32920
S126
I
Q
P
A
S
A
C
S
V
P
L
A
L
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.1
98.2
88.7
N.A.
78.9
78.9
N.A.
52.6
N.A.
23.2
22.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
41.5
98.2
90.1
N.A.
82.9
82.9
N.A.
62.1
N.A.
39.5
40.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
86.6
N.A.
53.3
60
N.A.
33.3
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
93.3
N.A.
66.6
73.3
N.A.
40
N.A.
6.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
23
0
0
0
0
12
23
12
12
45
% A
% Cys:
0
12
0
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
23
0
0
56
0
0
56
0
% D
% Glu:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
12
0
0
0
0
0
0
0
0
45
34
0
12
% G
% His:
12
0
0
12
0
12
0
12
0
12
0
12
0
0
12
% H
% Ile:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
23
34
0
0
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
12
0
0
0
23
0
0
0
56
0
12
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
23
0
12
12
0
0
12
12
12
12
23
0
0
% P
% Gln:
0
23
12
12
0
0
12
0
12
12
0
0
0
12
0
% Q
% Arg:
23
34
23
67
34
0
0
0
0
0
0
0
0
23
0
% R
% Ser:
45
12
0
0
34
45
67
56
0
67
12
12
23
0
12
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
23
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _