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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED10 All Species: 18.18
Human Site: T62 Identified Species: 30.77
UniProt: Q9BTT4 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BTT4 NP_115662.2 135 15688 T62 R Q Q L H D I T V P L E V F E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082923 135 15685 T62 R Q Q L H D I T V P L E V F E
Dog Lupus familis XP_849860 120 13463 T47 R Q Q L H D I T V P L E V F E
Cat Felis silvestris
Mouse Mus musculus Q9CXU0 135 15642 T62 R Q Q L H D I T V P L E V F E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511205 108 12440 F41 I S V P L E V F E Y I D Q G R
Chicken Gallus gallus Q5ZMC0 148 16345 R72 T E E L H H D R V P L E V G K
Frog Xenopus laevis Q6IP67 135 15597 T62 R Q Q L H D I T V P L E V F D
Zebra Danio Brachydanio rerio Q0VIA1 134 15419 N62 R Q Q L H D I N V P L E V F E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9GYU7 133 15638 V63 S Q V Q D V Y V P F E V F F D
Honey Bee Apis mellifera XP_624779 131 15142 H62 K S Q V Q D V H V P L E V F D
Nematode Worm Caenorhab. elegans P45966 173 20810 K101 K G T F S D K K V P L D L L P
Sea Urchin Strong. purpuratus XP_794222 137 15872 V67 E Q V Q D V Q V P L E L I Y E
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001150327 187 19967 Q93 L A E G C N I Q V P M E V V N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06213 157 17889 D78 Q S S L S K V D I P L E V V Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.2 74 N.A. 99.2 N.A. N.A. 77 21.6 93.3 88.1 N.A. 58.5 60 35.2 55.4
Protein Similarity: 100 N.A. 99.2 78.5 N.A. 100 N.A. N.A. 79.2 40.5 99.2 94.8 N.A. 76.3 80 52.5 81
P-Site Identity: 100 N.A. 100 100 N.A. 100 N.A. N.A. 0 46.6 93.3 93.3 N.A. 13.3 53.3 26.6 13.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. 26.6 66.6 100 93.3 N.A. 20 80 46.6 26.6
Percent
Protein Identity: N.A. 28.8 N.A. N.A. 24.8 N.A.
Protein Similarity: N.A. 42.2 N.A. N.A. 48.4 N.A.
P-Site Identity: N.A. 33.3 N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. 53.3 N.A. N.A. 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 15 58 8 8 0 0 0 15 0 0 22 % D
% Glu: 8 8 15 0 0 8 0 0 8 0 15 72 0 0 43 % E
% Phe: 0 0 0 8 0 0 0 8 0 8 0 0 8 58 0 % F
% Gly: 0 8 0 8 0 0 0 0 0 0 0 0 0 15 0 % G
% His: 0 0 0 0 50 8 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 50 0 8 0 8 0 8 0 0 % I
% Lys: 15 0 0 0 0 8 8 8 0 0 0 0 0 0 8 % K
% Leu: 8 0 0 58 8 0 0 0 0 8 72 8 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 8 0 0 0 0 15 79 0 0 0 0 8 % P
% Gln: 8 58 50 15 8 0 8 8 0 0 0 0 8 0 8 % Q
% Arg: 43 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % R
% Ser: 8 22 8 0 15 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 8 0 8 0 0 0 0 36 0 0 0 0 0 0 0 % T
% Val: 0 0 22 8 0 15 22 15 72 0 0 8 72 15 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 8 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _