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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED10 All Species: 43.03
Human Site: Y80 Identified Species: 72.82
UniProt: Q9BTT4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BTT4 NP_115662.2 135 15688 Y80 Q G R N P Q L Y T K E C L E R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082923 135 15685 Y80 Q G R N P Q L Y T K E C L E R
Dog Lupus familis XP_849860 120 13463 Y65 Q G R N P Q L Y T K E C L E R
Cat Felis silvestris
Mouse Mus musculus Q9CXU0 135 15642 Y80 Q G R N P Q L Y T K E C L E R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511205 108 12440 E59 L Y T K E C L E R A L A K N E
Chicken Gallus gallus Q5ZMC0 148 16345 M90 Q G R Q S K G M T Q K D L A T
Frog Xenopus laevis Q6IP67 135 15597 Y80 Q G R N P Q L Y T K E C L E R
Zebra Danio Brachydanio rerio Q0VIA1 134 15419 Y80 Q G R N P Q L Y T K E C L E R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9GYU7 133 15638 Y81 Q D K N P Q L Y T K D C V E K
Honey Bee Apis mellifera XP_624779 131 15142 Y80 Q G R N P Q L Y T K D C I E K
Nematode Worm Caenorhab. elegans P45966 173 20810 Y119 D G K N P C L Y S K H C M E K
Sea Urchin Strong. purpuratus XP_794222 137 15872 Y85 Q G K N P Q L Y T K D C M E R
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001150327 187 19967 F111 D G K N P D E F T R D V L N S
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q06213 157 17889 Y96 D G R N P D I Y T R E F V E A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.2 74 N.A. 99.2 N.A. N.A. 77 21.6 93.3 88.1 N.A. 58.5 60 35.2 55.4
Protein Similarity: 100 N.A. 99.2 78.5 N.A. 100 N.A. N.A. 79.2 40.5 99.2 94.8 N.A. 76.3 80 52.5 81
P-Site Identity: 100 N.A. 100 100 N.A. 100 N.A. N.A. 6.6 33.3 100 100 N.A. 66.6 80 53.3 80
P-Site Similarity: 100 N.A. 100 100 N.A. 100 N.A. N.A. 6.6 53.3 100 100 N.A. 93.3 100 80 100
Percent
Protein Identity: N.A. 28.8 N.A. N.A. 24.8 N.A.
Protein Similarity: N.A. 42.2 N.A. N.A. 48.4 N.A.
P-Site Identity: N.A. 33.3 N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. 60 N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 8 0 8 0 8 8 % A
% Cys: 0 0 0 0 0 15 0 0 0 0 0 72 0 0 0 % C
% Asp: 22 8 0 0 0 15 0 0 0 0 29 8 0 0 0 % D
% Glu: 0 0 0 0 8 0 8 8 0 0 50 0 0 79 8 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 8 0 0 0 % F
% Gly: 0 86 0 0 0 0 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 29 8 0 8 0 0 0 72 8 0 8 0 22 % K
% Leu: 8 0 0 0 0 0 79 0 0 0 8 0 58 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 15 0 0 % M
% Asn: 0 0 0 86 0 0 0 0 0 0 0 0 0 15 0 % N
% Pro: 0 0 0 0 86 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 72 0 0 8 0 65 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 65 0 0 0 0 0 8 15 0 0 0 0 50 % R
% Ser: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 8 % S
% Thr: 0 0 8 0 0 0 0 0 86 0 0 0 0 0 8 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 8 15 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 79 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _