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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI4K2A
All Species:
21.21
Human Site:
S22
Identified Species:
38.89
UniProt:
Q9BTU6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTU6
NP_060895.1
479
54022
S22
P
P
D
Y
T
F
P
S
G
S
G
A
H
F
P
Chimpanzee
Pan troglodytes
XP_001164880
481
54254
S22
P
P
D
Y
T
F
P
S
G
S
G
A
H
F
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543953
484
54388
S22
P
P
D
Y
T
F
P
S
C
S
G
S
H
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q2TBE6
479
54239
S22
P
P
E
Y
T
F
P
S
G
S
G
A
H
F
P
Rat
Rattus norvegicus
Q99M64
478
54286
S22
P
P
E
Y
T
F
P
S
V
S
G
A
H
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513782
411
46894
T22
P
A
L
F
V
L
G
T
A
E
M
N
I
F
L
Chicken
Gallus gallus
Q5ZIK0
479
53903
A30
G
P
P
A
G
R
A
A
P
G
G
A
V
R
L
Frog
Xenopus laevis
Q08B31
469
53187
Q22
T
E
Y
S
Y
Q
S
Q
C
S
P
G
A
T
V
Zebra Danio
Brachydanio rerio
Q6PE18
447
51424
A22
N
D
F
N
Y
G
P
A
E
P
T
S
P
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120474
466
53705
S40
L
V
D
L
S
I
T
S
N
N
C
L
P
I
N
Nematode Worm
Caenorhab. elegans
NP_508849
593
66195
S23
S
R
R
N
I
R
M
S
S
S
G
A
S
E
S
Sea Urchin
Strong. purpuratus
XP_801707
506
57844
L37
S
R
N
N
G
K
L
L
D
L
E
S
S
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42951
607
70198
P46
N
P
I
T
H
A
S
P
G
V
G
S
N
A
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
N.A.
97.5
N.A.
95.4
94.9
N.A.
59.7
60.1
78
76.6
N.A.
N.A.
55.5
40.2
52.3
Protein Similarity:
100
98.3
N.A.
98.1
N.A.
97.6
96.8
N.A.
70.3
72.4
83.9
83.7
N.A.
N.A.
69.9
50.2
66.8
P-Site Identity:
100
100
N.A.
86.6
N.A.
93.3
86.6
N.A.
13.3
20
6.6
6.6
N.A.
N.A.
13.3
26.6
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
93.3
N.A.
26.6
26.6
6.6
20
N.A.
N.A.
26.6
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
8
8
16
8
0
0
47
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
16
0
8
0
0
0
0
% C
% Asp:
0
8
31
0
0
0
0
0
8
0
0
0
0
8
0
% D
% Glu:
0
8
16
0
0
0
0
0
8
8
8
0
0
8
8
% E
% Phe:
0
0
8
8
0
39
0
0
0
0
0
0
0
47
0
% F
% Gly:
8
0
0
0
16
8
8
0
31
8
62
8
0
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
39
0
0
% H
% Ile:
0
0
8
0
8
8
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
8
8
0
8
8
8
0
8
0
8
0
0
16
% L
% Met:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% M
% Asn:
16
0
8
24
0
0
0
0
8
8
0
8
8
0
8
% N
% Pro:
47
54
8
0
0
0
47
8
8
8
8
0
16
0
39
% P
% Gln:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
8
% Q
% Arg:
0
16
8
0
0
16
0
0
0
0
0
0
0
16
0
% R
% Ser:
16
0
0
8
8
0
16
54
8
54
0
31
16
0
8
% S
% Thr:
8
0
0
8
39
0
8
8
0
0
8
0
0
8
0
% T
% Val:
0
8
0
0
8
0
0
0
8
8
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
39
16
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _