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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PI4K2A All Species: 20.91
Human Site: T19 Identified Species: 38.33
UniProt: Q9BTU6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BTU6 NP_060895.1 479 54022 T19 R A Q P P D Y T F P S G S G A
Chimpanzee Pan troglodytes XP_001164880 481 54254 T19 R A Q P P D Y T F P S G S G A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543953 484 54388 T19 R A Q P P D Y T F P S C S G S
Cat Felis silvestris
Mouse Mus musculus Q2TBE6 479 54239 T19 R A Q P P E Y T F P S G S G A
Rat Rattus norvegicus Q99M64 478 54286 T19 R A Q P P E Y T F P S V S G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513782 411 46894 V19 S G Q P A L F V L G T A E M N
Chicken Gallus gallus Q5ZIK0 479 53903 G27 L H A G P P A G R A A P G G A
Frog Xenopus laevis Q08B31 469 53187 Y19 R D Q T E Y S Y Q S Q C S P G
Zebra Danio Brachydanio rerio Q6PE18 447 51424 Y19 R D S N D F N Y G P A E P T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001120474 466 53705 S37 T D A L V D L S I T S N N C L
Nematode Worm Caenorhab. elegans NP_508849 593 66195 I20 I S P S R R N I R M S S S G A
Sea Urchin Strong. purpuratus XP_801707 506 57844 G34 Y S D S R N N G K L L D L E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P42951 607 70198 H43 K S K N P I T H A S P G V G S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.9 N.A. 97.5 N.A. 95.4 94.9 N.A. 59.7 60.1 78 76.6 N.A. N.A. 55.5 40.2 52.3
Protein Similarity: 100 98.3 N.A. 98.1 N.A. 97.6 96.8 N.A. 70.3 72.4 83.9 83.7 N.A. N.A. 69.9 50.2 66.8
P-Site Identity: 100 100 N.A. 86.6 N.A. 93.3 86.6 N.A. 13.3 20 20 13.3 N.A. N.A. 13.3 26.6 0
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 93.3 N.A. 26.6 26.6 20 26.6 N.A. N.A. 26.6 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 39 16 0 8 0 8 0 8 8 16 8 0 0 47 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 16 0 8 0 % C
% Asp: 0 24 8 0 8 31 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 0 0 0 8 16 0 0 0 0 0 8 8 8 0 % E
% Phe: 0 0 0 0 0 8 8 0 39 0 0 0 0 0 0 % F
% Gly: 0 8 0 8 0 0 0 16 8 8 0 31 8 62 8 % G
% His: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 8 0 8 8 0 0 0 0 0 0 % I
% Lys: 8 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % K
% Leu: 8 0 0 8 0 8 8 0 8 8 8 0 8 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % M
% Asn: 0 0 0 16 0 8 24 0 0 0 0 8 8 0 8 % N
% Pro: 0 0 8 47 54 8 0 0 0 47 8 8 8 8 0 % P
% Gln: 0 0 54 0 0 0 0 0 8 0 8 0 0 0 0 % Q
% Arg: 54 0 0 0 16 8 0 0 16 0 0 0 0 0 0 % R
% Ser: 8 24 8 16 0 0 8 8 0 16 54 8 54 0 31 % S
% Thr: 8 0 0 8 0 0 8 39 0 8 8 0 0 8 0 % T
% Val: 0 0 0 0 8 0 0 8 0 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 8 39 16 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _