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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM43 All Species: 11.21
Human Site: S209 Identified Species: 22.42
UniProt: Q9BTV4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BTV4 NP_077310.1 400 44876 S209 N F K S L S L S K L E D P H V
Chimpanzee Pan troglodytes XP_516299 400 44829 S209 N F K S L S L S K L E D P H V
Rhesus Macaque Macaca mulatta XP_001090994 400 44870 S209 N F K P L S L S K L E D P H V
Dog Lupus familis XP_541751 400 44872 A209 N F K P L S L A K L D D P H V
Cat Felis silvestris
Mouse Mus musculus Q9DBS1 400 44765 A209 N F K A L S L A K L E D P H V
Rat Rattus norvegicus Q5XIP9 400 44756 A209 N F K P L S L A K L E D P H V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507428 248 28322 S80 R A L R T A T S L A E G L S L
Chicken Gallus gallus XP_414378 400 44849 A209 D F K Q L S L A H L E D P H A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998403 282 31264 H114 Y H T P N P Q H P E V G D V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VSB9 376 42755 I205 G V K L H L G I Y Y H T N D V
Honey Bee Apis mellifera XP_624625 406 46544 D219 D F V E V T S D E R P E R K D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798642 410 46142 T215 N F D P Y F T T Q Q P S N P N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 96.7 92.5 N.A. 93 91.5 N.A. 48.2 70 N.A. 37.7 N.A. 32.7 34.2 N.A. 31.7
Protein Similarity: 100 99.5 97.7 96.7 N.A. 97 95.7 N.A. 53.7 85.5 N.A. 52.5 N.A. 50.5 55.1 N.A. 52.4
P-Site Identity: 100 100 93.3 80 N.A. 86.6 86.6 N.A. 13.3 66.6 N.A. 0 N.A. 13.3 6.6 N.A. 13.3
P-Site Similarity: 100 100 93.3 93.3 N.A. 100 93.3 N.A. 26.6 80 N.A. 0 N.A. 13.3 40 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 9 0 34 0 9 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 0 9 0 0 0 0 9 0 0 9 59 9 9 9 % D
% Glu: 0 0 0 9 0 0 0 0 9 9 59 9 0 0 0 % E
% Phe: 0 75 0 0 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 0 9 0 0 0 0 17 0 0 0 % G
% His: 0 9 0 0 9 0 0 9 9 0 9 0 0 59 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % I
% Lys: 0 0 67 0 0 0 0 0 50 0 0 0 0 9 0 % K
% Leu: 0 0 9 9 59 9 59 0 9 59 0 0 9 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 59 0 0 0 9 0 0 0 0 0 0 0 17 0 9 % N
% Pro: 0 0 0 42 0 9 0 0 9 0 17 0 59 9 0 % P
% Gln: 0 0 0 9 0 0 9 0 9 9 0 0 0 0 0 % Q
% Arg: 9 0 0 9 0 0 0 0 0 9 0 0 9 0 9 % R
% Ser: 0 0 0 17 0 59 9 34 0 0 0 9 0 9 0 % S
% Thr: 0 0 9 0 9 9 17 9 0 0 0 9 0 0 0 % T
% Val: 0 9 9 0 9 0 0 0 0 0 9 0 0 9 59 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 0 9 0 0 0 9 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _