KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM43
All Species:
28.79
Human Site:
S228
Identified Species:
57.58
UniProt:
Q9BTV4
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTV4
NP_077310.1
400
44876
S228
R
G
D
F
F
Y
H
S
E
N
P
K
Y
P
E
Chimpanzee
Pan troglodytes
XP_516299
400
44829
S228
R
G
D
F
F
Y
H
S
E
N
P
K
Y
P
E
Rhesus Macaque
Macaca mulatta
XP_001090994
400
44870
S228
R
G
D
F
F
Y
H
S
E
N
P
K
Y
P
E
Dog
Lupus familis
XP_541751
400
44872
S228
R
G
D
Y
F
Y
H
S
E
N
P
K
Y
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBS1
400
44765
S228
R
G
D
F
F
Y
H
S
E
N
P
K
Y
P
E
Rat
Rattus norvegicus
Q5XIP9
400
44756
S228
R
G
D
F
F
Y
H
S
E
N
P
K
Y
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507428
248
28322
V97
S
L
D
S
I
H
S
V
A
P
E
N
E
G
R
Chicken
Gallus gallus
XP_414378
400
44849
S228
G
G
D
Y
F
Y
H
S
E
N
P
R
R
P
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998403
282
31264
G131
F
A
Y
A
G
L
S
G
D
G
L
Y
P
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSB9
376
42755
L222
P
E
V
G
D
L
R
L
L
F
S
F
A
G
M
Honey Bee
Apis mellifera
XP_624625
406
46544
S237
H
S
G
L
Y
Y
H
S
S
N
L
W
K
P
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798642
410
46142
L234
N
G
F
Y
H
F
S
L
D
I
N
R
P
M
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.7
92.5
N.A.
93
91.5
N.A.
48.2
70
N.A.
37.7
N.A.
32.7
34.2
N.A.
31.7
Protein Similarity:
100
99.5
97.7
96.7
N.A.
97
95.7
N.A.
53.7
85.5
N.A.
52.5
N.A.
50.5
55.1
N.A.
52.4
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
73.3
N.A.
0
N.A.
0
33.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
86.6
N.A.
6.6
N.A.
0
46.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
0
0
0
9
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
67
0
9
0
0
0
17
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
59
0
9
0
9
0
59
% E
% Phe:
9
0
9
42
59
9
0
0
0
9
0
9
0
0
0
% F
% Gly:
9
67
9
9
9
0
0
9
0
9
0
0
0
25
0
% G
% His:
9
0
0
0
9
9
67
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
50
9
0
9
% K
% Leu:
0
9
0
9
0
17
0
17
9
0
17
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% M
% Asn:
9
0
0
0
0
0
0
0
0
67
9
9
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
9
59
0
17
67
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
50
0
0
0
0
0
9
0
0
0
0
17
9
0
9
% R
% Ser:
9
9
0
9
0
0
25
67
9
0
9
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
9
25
9
67
0
0
0
0
0
9
50
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _