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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM43
All Species:
25.76
Human Site:
S244
Identified Species:
51.52
UniProt:
Q9BTV4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTV4
NP_077310.1
400
44876
S244
G
D
L
R
V
S
F
S
Y
A
G
L
S
G
D
Chimpanzee
Pan troglodytes
XP_516299
400
44829
S244
G
D
L
R
V
S
F
S
Y
A
G
L
S
G
D
Rhesus Macaque
Macaca mulatta
XP_001090994
400
44870
S244
G
D
L
R
I
S
F
S
Y
A
G
L
S
S
D
Dog
Lupus familis
XP_541751
400
44872
S244
G
D
V
R
V
S
F
S
Y
A
G
L
S
G
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBS1
400
44765
S244
G
D
V
R
V
S
F
S
Y
A
G
L
S
S
D
Rat
Rattus norvegicus
Q5XIP9
400
44756
S244
G
D
V
R
V
S
F
S
Y
A
G
L
S
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507428
248
28322
R113
V
H
L
I
G
S
L
R
T
S
K
L
L
S
D
Chicken
Gallus gallus
XP_414378
400
44849
F244
G
D
L
R
V
S
F
F
Y
A
G
L
S
G
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998403
282
31264
Q147
H
K
V
S
V
V
A
Q
Q
H
Q
Q
Q
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSB9
376
42755
G238
G
E
V
F
S
V
V
G
K
L
S
G
N
K
L
Honey Bee
Apis mellifera
XP_624625
406
46544
S253
G
D
I
R
I
Q
F
S
Y
A
G
K
G
G
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798642
410
46142
Y250
E
V
R
V
T
F
S
Y
A
G
V
S
G
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.7
92.5
N.A.
93
91.5
N.A.
48.2
70
N.A.
37.7
N.A.
32.7
34.2
N.A.
31.7
Protein Similarity:
100
99.5
97.7
96.7
N.A.
97
95.7
N.A.
53.7
85.5
N.A.
52.5
N.A.
50.5
55.1
N.A.
52.4
P-Site Identity:
100
100
86.6
93.3
N.A.
86.6
86.6
N.A.
26.6
86.6
N.A.
6.6
N.A.
6.6
66.6
N.A.
0
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
33.3
86.6
N.A.
13.3
N.A.
26.6
80
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
9
67
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
67
0
0
0
0
0
0
0
0
0
0
0
0
67
% D
% Glu:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
9
0
9
67
9
0
0
0
0
0
0
0
% F
% Gly:
75
0
0
0
9
0
0
9
0
9
67
9
17
42
0
% G
% His:
9
9
0
0
0
0
0
0
0
9
0
0
0
0
9
% H
% Ile:
0
0
9
9
17
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
0
0
0
9
0
9
9
0
9
0
% K
% Leu:
0
0
42
0
0
0
9
0
0
9
0
67
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
9
0
9
9
0
9
9
9
9
0
% Q
% Arg:
0
0
9
67
0
0
0
9
0
0
0
0
0
0
9
% R
% Ser:
0
0
0
9
9
67
9
59
0
9
9
9
59
34
0
% S
% Thr:
0
0
0
0
9
0
0
0
9
0
0
0
0
0
0
% T
% Val:
9
9
42
9
59
17
9
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
67
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _