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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CABLES2
All Species:
10.91
Human Site:
S219
Identified Species:
21.82
UniProt:
Q9BTV7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTV7
NP_112492.2
478
52235
S219
R
H
P
S
G
G
V
S
V
S
S
E
M
V
F
Chimpanzee
Pan troglodytes
XP_512059
702
76038
K449
S
T
G
A
V
S
L
K
E
I
I
G
L
E
G
Rhesus Macaque
Macaca mulatta
XP_001115094
400
44686
A165
D
G
K
V
V
S
Y
A
K
F
L
Y
P
T
N
Dog
Lupus familis
XP_855204
432
47740
A188
D
G
K
V
V
S
Y
A
K
F
L
Y
P
T
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8K3M5
481
52692
S222
R
H
P
S
G
G
V
S
V
S
S
E
M
V
F
Rat
Rattus norvegicus
XP_001059501
427
47203
V189
L
G
A
D
G
K
V
V
S
Y
A
K
F
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506144
362
41389
K128
G
K
V
V
S
Y
A
K
F
L
Y
P
T
N
A
Chicken
Gallus gallus
XP_417406
469
52163
S210
R
H
P
S
G
G
V
S
V
S
T
E
M
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919825
505
55506
S251
R
H
S
S
G
G
G
S
D
M
V
P
G
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610890
717
79307
P428
R
N
P
S
T
S
R
P
L
S
S
I
N
D
A
Honey Bee
Apis mellifera
XP_623648
562
63688
Q283
R
R
K
N
I
S
S
Q
R
P
L
S
A
I
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790638
413
47121
R179
S
H
F
L
V
P
S
R
D
I
S
L
I
L
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.8
79.5
75.3
N.A.
87.7
78.2
N.A.
64.8
76.9
N.A.
51.4
N.A.
26
33.8
N.A.
30.5
Protein Similarity:
100
50.4
80.5
78.8
N.A.
90.6
81.1
N.A.
69.6
82.8
N.A.
63.3
N.A.
41.2
49.2
N.A.
49.1
P-Site Identity:
100
0
0
0
N.A.
100
13.3
N.A.
0
86.6
N.A.
40
N.A.
33.3
6.6
N.A.
20
P-Site Similarity:
100
20
6.6
6.6
N.A.
100
40
N.A.
0
93.3
N.A.
46.6
N.A.
46.6
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
0
0
9
17
0
0
9
0
9
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
0
9
0
0
0
0
17
0
0
0
0
9
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
0
0
25
0
9
9
% E
% Phe:
0
0
9
0
0
0
0
0
9
17
0
0
9
0
25
% F
% Gly:
9
25
9
0
42
34
9
0
0
0
0
9
9
0
9
% G
% His:
0
42
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
17
9
9
9
9
0
% I
% Lys:
0
9
25
0
0
9
0
17
17
0
0
9
0
0
0
% K
% Leu:
9
0
0
9
0
0
9
0
9
9
25
9
9
25
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
25
0
0
% M
% Asn:
0
9
0
9
0
0
0
0
0
0
0
0
9
9
25
% N
% Pro:
0
0
34
0
0
9
0
9
0
9
0
17
17
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Q
% Arg:
50
9
0
0
0
0
9
9
9
0
0
0
0
0
0
% R
% Ser:
17
0
9
42
9
42
17
34
9
34
34
9
0
0
0
% S
% Thr:
0
9
0
0
9
0
0
0
0
0
9
0
9
17
0
% T
% Val:
0
0
9
25
34
0
34
9
25
0
9
0
0
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
17
0
0
9
9
17
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _