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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CABLES2 All Species: 13.94
Human Site: T125 Identified Species: 27.88
UniProt: Q9BTV7 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BTV7 NP_112492.2 478 52235 T125 Q R Q R K R V T S Q R C S L E
Chimpanzee Pan troglodytes XP_512059 702 76038 I355 Q R S R R R L I S Q R S S L E
Rhesus Macaque Macaca mulatta XP_001115094 400 44686 S72 A Q R T K H T S G S P R H K G
Dog Lupus familis XP_855204 432 47740 S95 V Q R T K H I S G S P R H K G
Cat Felis silvestris
Mouse Mus musculus Q8K3M5 481 52692 T128 Q R Q R R R V T S Q R C S L E
Rat Rattus norvegicus XP_001059501 427 47203 S96 V Q R T K H A S G S P R H K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506144 362 41389 G35 Q R T K H L S G S P R H K S L
Chicken Gallus gallus XP_417406 469 52163 S117 S Q L K R F I S Q R C S L D F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001919825 505 55506 S158 P R N T A L G S S K S P S Q F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610890 717 79307 P278 G A G S K L L P L R E R T F S
Honey Bee Apis mellifera XP_623648 562 63688 S131 E R N Y P Q L S T G F H S S F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790638 413 47121 K86 G F Q I P V A K T F R Q R M C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42.8 79.5 75.3 N.A. 87.7 78.2 N.A. 64.8 76.9 N.A. 51.4 N.A. 26 33.8 N.A. 30.5
Protein Similarity: 100 50.4 80.5 78.8 N.A. 90.6 81.1 N.A. 69.6 82.8 N.A. 63.3 N.A. 41.2 49.2 N.A. 49.1
P-Site Identity: 100 66.6 6.6 6.6 N.A. 93.3 6.6 N.A. 26.6 0 N.A. 20 N.A. 6.6 13.3 N.A. 13.3
P-Site Similarity: 100 80 26.6 33.3 N.A. 100 26.6 N.A. 33.3 40 N.A. 33.3 N.A. 26.6 46.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 9 0 17 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 17 0 0 9 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % D
% Glu: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 25 % E
% Phe: 0 9 0 0 0 9 0 0 0 9 9 0 0 9 25 % F
% Gly: 17 0 9 0 0 0 9 9 25 9 0 0 0 0 25 % G
% His: 0 0 0 0 9 25 0 0 0 0 0 17 25 0 0 % H
% Ile: 0 0 0 9 0 0 17 9 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 17 42 0 0 9 0 9 0 0 9 25 0 % K
% Leu: 0 0 9 0 0 25 25 0 9 0 0 0 9 25 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 0 0 17 0 0 9 0 9 25 9 0 0 0 % P
% Gln: 34 34 25 0 0 9 0 0 9 25 0 9 0 9 0 % Q
% Arg: 0 50 25 25 25 25 0 0 0 17 42 34 9 0 0 % R
% Ser: 9 0 9 9 0 0 9 50 42 25 9 17 42 17 9 % S
% Thr: 0 0 9 34 0 0 9 17 17 0 0 0 9 0 0 % T
% Val: 17 0 0 0 0 9 17 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _