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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBCD All Species: 13.33
Human Site: S719 Identified Species: 29.33
UniProt: Q9BTW9 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BTW9 NP_005984.3 1192 132528 S719 R H L H L I S S H S R Q Q M K
Chimpanzee Pan troglodytes XP_001168814 1248 138629 S719 R H L H L I S S H S R Q Q M K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548804 946 103214 Q541 T L P R V L L Q G R L Q Q V L
Cat Felis silvestris
Mouse Mus musculus Q8BYA0 1196 133303 S721 R S L H L V S S H S R Q Q I K
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZI87 1019 113644 G615 R L L P L S V G T D L H T R H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922584 1191 132992 S716 K N L H L F S S G V R R G I Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608648 1189 134492 I704 K V I D S C L I T K S N A I R
Honey Bee Apis mellifera XP_001121704 1097 125112 Q635 I E T I C D W Q N L L E E C L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190837 898 100451 T494 A V G N R T N T Y L N I S S Y
Poplar Tree Populus trichocarpa XP_002320715 1253 139607 R739 K A L E H F V R A Y L V T T N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191633 1254 139897 N743 T E N L R H P N S Q I Q N A A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.9 N.A. 52 N.A. 81.8 N.A. N.A. N.A. 60.4 N.A. 64.4 N.A. 40.5 39.5 N.A. 39.2
Protein Similarity: 100 94.4 N.A. 62.7 N.A. 88.4 N.A. N.A. N.A. 72 N.A. 79.4 N.A. 60.3 58.6 N.A. 53.4
P-Site Identity: 100 100 N.A. 13.3 N.A. 80 N.A. N.A. N.A. 20 N.A. 40 N.A. 0 0 N.A. 0
P-Site Similarity: 100 100 N.A. 33.3 N.A. 93.3 N.A. N.A. N.A. 20 N.A. 73.3 N.A. 26.6 20 N.A. 26.6
Percent
Protein Identity: 34.9 N.A. N.A. 35 N.A. N.A.
Protein Similarity: 55.3 N.A. N.A. 54.9 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 0 0 10 0 0 0 10 10 10 % A
% Cys: 0 0 0 0 10 10 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 0 10 0 10 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 19 0 10 0 0 0 0 0 0 0 10 10 0 0 % E
% Phe: 0 0 0 0 0 19 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 0 10 19 0 0 0 10 0 0 % G
% His: 0 19 0 37 10 10 0 0 28 0 0 10 0 0 10 % H
% Ile: 10 0 10 10 0 19 0 10 0 0 10 10 0 28 0 % I
% Lys: 28 0 0 0 0 0 0 0 0 10 0 0 0 0 28 % K
% Leu: 0 19 55 10 46 10 19 0 0 19 37 0 0 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 19 0 % M
% Asn: 0 10 10 10 0 0 10 10 10 0 10 10 10 0 10 % N
% Pro: 0 0 10 10 0 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 19 0 10 0 46 37 0 10 % Q
% Arg: 37 0 0 10 19 0 0 10 0 10 37 10 0 10 10 % R
% Ser: 0 10 0 0 10 10 37 37 10 28 10 0 10 10 0 % S
% Thr: 19 0 10 0 0 10 0 10 19 0 0 0 19 10 0 % T
% Val: 0 19 0 0 10 10 19 0 0 10 0 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _