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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBCD All Species: 9.7
Human Site: S952 Identified Species: 21.33
UniProt: Q9BTW9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BTW9 NP_005984.3 1192 132528 S952 L E K L F P R S D V A S V N W
Chimpanzee Pan troglodytes XP_001168814 1248 138629 S952 L E K L F P R S D V A S V N W
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548804 946 103214 F760 R Y S T Q S L F E Y M K G I Q
Cat Felis silvestris
Mouse Mus musculus Q8BYA0 1196 133303 S955 L E S L F P R S D V A T V N W
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZI87 1019 113644 V834 E I C Q T V G V K G E G S Q E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922584 1191 132992 E950 L L S I F P P E T G N S L N W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608648 1189 134492 I940 E H S K L L E I F P A D A D S
Honey Bee Apis mellifera XP_001121704 1097 125112 Y856 E L K T I F P Y D E C K E N I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190837 898 100451 N713 I K G L E D P N E M G R M G A
Poplar Tree Populus trichocarpa XP_002320715 1253 139607 P982 E N L E E I V P N E T D L K W
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191633 1254 139897 P983 E K L E E I L P N K A N L Q W
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.9 N.A. 52 N.A. 81.8 N.A. N.A. N.A. 60.4 N.A. 64.4 N.A. 40.5 39.5 N.A. 39.2
Protein Similarity: 100 94.4 N.A. 62.7 N.A. 88.4 N.A. N.A. N.A. 72 N.A. 79.4 N.A. 60.3 58.6 N.A. 53.4
P-Site Identity: 100 100 N.A. 0 N.A. 86.6 N.A. N.A. N.A. 0 N.A. 40 N.A. 6.6 20 N.A. 6.6
P-Site Similarity: 100 100 N.A. 6.6 N.A. 93.3 N.A. N.A. N.A. 0 N.A. 53.3 N.A. 13.3 20 N.A. 46.6
Percent
Protein Identity: 34.9 N.A. N.A. 35 N.A. N.A.
Protein Similarity: 55.3 N.A. N.A. 54.9 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 46 0 10 0 10 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 37 0 0 19 0 10 0 % D
% Glu: 46 28 0 19 28 0 10 10 19 19 10 0 10 0 10 % E
% Phe: 0 0 0 0 37 10 0 10 10 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 0 0 10 0 0 19 10 10 10 10 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 10 10 0 10 10 19 0 10 0 0 0 0 0 10 10 % I
% Lys: 0 19 28 10 0 0 0 0 10 10 0 19 0 10 0 % K
% Leu: 37 19 19 37 10 10 19 0 0 0 0 0 28 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 10 0 10 0 0 % M
% Asn: 0 10 0 0 0 0 0 10 19 0 10 10 0 46 0 % N
% Pro: 0 0 0 0 0 37 28 19 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 10 10 0 0 0 0 0 0 0 0 19 10 % Q
% Arg: 10 0 0 0 0 0 28 0 0 0 0 10 0 0 0 % R
% Ser: 0 0 37 0 0 10 0 28 0 0 0 28 10 0 10 % S
% Thr: 0 0 0 19 10 0 0 0 10 0 10 10 0 0 0 % T
% Val: 0 0 0 0 0 10 10 10 0 28 0 0 28 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 55 % W
% Tyr: 0 10 0 0 0 0 0 10 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _