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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBCD All Species: 16.36
Human Site: T1127 Identified Species: 36
UniProt: Q9BTW9 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BTW9 NP_005984.3 1192 132528 T1127 R F P L I R K T T A S Q V Y E
Chimpanzee Pan troglodytes XP_001168814 1248 138629 T1165 R F P L I R K T T A S Q V Y E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548804 946 103214 V908 V L E E V M A V L G A T A W D
Cat Felis silvestris
Mouse Mus musculus Q8BYA0 1196 133303 S1130 P F P V I R K S T A S Q V Y E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZI87 1019 113644 A981 T Q L L A L P A Y Q Y Y V L L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922584 1191 132992 T1125 P F P L I R K T T A S Q V Y E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608648 1189 134492 T1114 Q H V H V R K T A A T K L Y E
Honey Bee Apis mellifera XP_001121704 1097 125112 V1031 K Y K C I R K V A A T R T Y E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190837 898 100451 K860 L A Q Q A S E K I D R T R L C
Poplar Tree Populus trichocarpa XP_002320715 1253 139607 A1161 R Y P K I R K A S A E Q V Y I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_191633 1254 139897 A1162 R Y P M I R K A A A E Q V Y L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.9 N.A. 52 N.A. 81.8 N.A. N.A. N.A. 60.4 N.A. 64.4 N.A. 40.5 39.5 N.A. 39.2
Protein Similarity: 100 94.4 N.A. 62.7 N.A. 88.4 N.A. N.A. N.A. 72 N.A. 79.4 N.A. 60.3 58.6 N.A. 53.4
P-Site Identity: 100 100 N.A. 0 N.A. 80 N.A. N.A. N.A. 13.3 N.A. 93.3 N.A. 40 40 N.A. 0
P-Site Similarity: 100 100 N.A. 26.6 N.A. 93.3 N.A. N.A. N.A. 13.3 N.A. 93.3 N.A. 73.3 66.6 N.A. 6.6
Percent
Protein Identity: 34.9 N.A. N.A. 35 N.A. N.A.
Protein Similarity: 55.3 N.A. N.A. 54.9 N.A. N.A.
P-Site Identity: 60 N.A. N.A. 60 N.A. N.A.
P-Site Similarity: 73.3 N.A. N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 19 0 10 28 28 73 10 0 10 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % D
% Glu: 0 0 10 10 0 0 10 0 0 0 19 0 0 0 55 % E
% Phe: 0 37 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % G
% His: 0 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 64 0 0 0 10 0 0 0 0 0 10 % I
% Lys: 10 0 10 10 0 0 73 10 0 0 0 10 0 0 0 % K
% Leu: 10 10 10 37 0 10 0 0 10 0 0 0 10 19 19 % L
% Met: 0 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 19 0 55 0 0 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 10 10 10 10 0 0 0 0 0 10 0 55 0 0 0 % Q
% Arg: 37 0 0 0 0 73 0 0 0 0 10 10 10 0 0 % R
% Ser: 0 0 0 0 0 10 0 10 10 0 37 0 0 0 0 % S
% Thr: 10 0 0 0 0 0 0 37 37 0 19 19 10 0 0 % T
% Val: 10 0 10 10 19 0 0 19 0 0 0 0 64 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % W
% Tyr: 0 28 0 0 0 0 0 0 10 0 10 10 0 73 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _