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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM48
All Species:
18.48
Human Site:
S339
Identified Species:
40.67
UniProt:
Q9BTX1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTX1
NP_060557.2
674
76305
S339
L
Q
D
L
M
L
L
S
Q
Y
S
P
S
R
R
Chimpanzee
Pan troglodytes
XP_513417
776
87618
S441
L
Q
D
L
M
L
L
S
Q
Y
S
P
S
R
R
Rhesus Macaque
Macaca mulatta
XP_001091911
530
59703
L203
I
I
Q
Q
Y
K
F
L
R
F
R
R
S
L
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCB1
673
75391
S340
L
Q
D
L
M
L
L
S
Q
Y
S
P
S
R
R
Rat
Rattus norvegicus
Q6AXN4
673
75694
S340
L
Q
D
L
M
L
L
S
Q
Y
S
P
S
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518195
431
47121
W102
P
P
H
Q
V
L
G
W
R
V
A
T
S
V
A
Chicken
Gallus gallus
XP_001235442
684
77153
S350
L
Q
D
L
M
L
L
S
Q
Y
S
P
V
R
R
Frog
Xenopus laevis
Q6AX31
660
74320
R333
L
S
Q
Y
S
P
S
R
R
Q
E
V
F
S
L
Zebra Danio
Brachydanio rerio
Q7SZC5
671
74423
R336
S
Q
H
S
P
S
R
R
Q
E
V
F
S
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCG4
578
65368
F251
V
T
N
V
R
L
L
F
Y
G
Y
L
L
T
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784037
756
85199
T428
L
S
A
T
P
Y
G
T
P
A
D
Y
P
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86
76.4
N.A.
N.A.
87
86.9
N.A.
20.4
67.8
56.8
53.5
N.A.
22.7
N.A.
N.A.
28.1
Protein Similarity:
100
86.2
77.3
N.A.
N.A.
92.1
92.5
N.A.
33.5
79.3
72.4
72.2
N.A.
43.4
N.A.
N.A.
45.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
100
100
N.A.
13.3
93.3
6.6
20
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
26.6
N.A.
N.A.
100
100
N.A.
33.3
93.3
13.3
20
N.A.
33.3
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
10
10
0
0
10
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
46
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
10
0
10
0
10
10
0
0
% F
% Gly:
0
0
0
0
0
0
19
0
0
10
0
0
0
0
0
% G
% His:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
64
0
0
46
0
64
55
10
0
0
0
10
10
19
19
% L
% Met:
0
0
0
0
46
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
0
0
19
10
0
0
10
0
0
46
10
0
10
% P
% Gln:
0
55
19
19
0
0
0
0
55
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
10
19
28
0
10
10
0
46
46
% R
% Ser:
10
19
0
10
10
10
10
46
0
0
46
0
64
10
10
% S
% Thr:
0
10
0
10
0
0
0
10
0
0
0
10
0
10
0
% T
% Val:
10
0
0
10
10
0
0
0
0
10
10
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
10
0
0
10
46
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _