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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTPAL
All Species:
32.12
Human Site:
S260
Identified Species:
58.89
UniProt:
Q9BTX7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTX7
NP_001034288.1
342
38515
S260
L
H
G
S
D
L
N
S
L
H
T
N
L
P
R
Chimpanzee
Pan troglodytes
XP_514665
342
38428
S260
L
H
G
S
D
L
N
S
L
H
T
N
L
P
S
Rhesus Macaque
Macaca mulatta
XP_001110493
342
38437
S260
L
H
G
S
D
L
N
S
L
H
A
N
L
P
R
Dog
Lupus familis
XP_534426
342
38407
S260
L
H
G
S
D
L
N
S
L
H
T
N
L
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3D0
343
38817
S261
L
H
G
S
D
L
N
S
L
H
T
N
L
P
R
Rat
Rattus norvegicus
A6JUQ6
327
37898
S235
L
H
G
N
N
L
N
S
L
H
Q
L
I
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510973
445
49726
S250
L
H
G
S
D
L
N
S
L
H
S
N
L
P
R
Chicken
Gallus gallus
NP_001026025
300
33914
A220
G
F
P
I
R
I
K
A
V
N
I
I
N
E
P
Frog
Xenopus laevis
Q5M7E1
332
38511
S235
L
H
G
N
N
L
N
S
L
H
Q
L
I
H
P
Zebra Danio
Brachydanio rerio
Q5SPP0
329
38101
S235
M
H
G
N
N
L
N
S
L
H
Q
L
I
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03606
719
81064
H501
T
N
C
G
L
G
G
H
V
P
K
S
M
Y
L
Sea Urchin
Strong. purpuratus
XP_780795
286
33208
D205
I
N
E
S
L
L
F
D
G
A
F
T
I
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33324
310
36055
I216
E
R
M
G
K
F
Y
I
I
H
S
P
F
G
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.5
94.7
N.A.
94.1
33.3
N.A.
61.5
73.3
33.6
33.3
N.A.
N.A.
N.A.
20.4
31.5
Protein Similarity:
100
99.7
99.1
96.1
N.A.
98.2
49.4
N.A.
66.2
79.2
49.1
49.7
N.A.
N.A.
N.A.
30
50.2
P-Site Identity:
100
93.3
93.3
100
N.A.
100
53.3
N.A.
93.3
0
53.3
46.6
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
73.3
N.A.
100
26.6
73.3
73.3
N.A.
N.A.
N.A.
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
8
8
0
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
47
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
8
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
8
0
0
0
8
8
0
0
0
8
0
8
0
8
% F
% Gly:
8
0
70
16
0
8
8
0
8
0
0
0
0
8
0
% G
% His:
0
70
0
0
0
0
0
8
0
77
0
0
0
16
0
% H
% Ile:
8
0
0
8
0
8
0
8
8
0
8
8
31
8
0
% I
% Lys:
0
0
0
0
8
0
8
0
0
0
8
0
0
0
8
% K
% Leu:
62
0
0
0
16
77
0
0
70
0
0
24
47
8
8
% L
% Met:
8
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
16
0
24
24
0
70
0
0
8
0
47
8
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
8
0
8
0
47
31
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
24
0
0
0
0
% Q
% Arg:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
39
% R
% Ser:
0
0
0
54
0
0
0
70
0
0
16
8
0
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
31
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _