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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTPAL
All Species:
31.21
Human Site:
T159
Identified Species:
57.22
UniProt:
Q9BTX7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTX7
NP_001034288.1
342
38515
T159
I
P
S
N
Y
P
I
T
E
N
I
R
A
I
Y
Chimpanzee
Pan troglodytes
XP_514665
342
38428
T159
I
P
S
N
Y
P
I
T
E
N
I
R
A
I
Y
Rhesus Macaque
Macaca mulatta
XP_001110493
342
38437
T159
I
P
S
N
Y
P
I
T
E
N
I
R
A
I
Y
Dog
Lupus familis
XP_534426
342
38407
T159
I
P
S
N
Y
P
I
T
E
N
I
R
A
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9D3D0
343
38817
T160
I
P
S
N
Y
P
I
T
E
N
I
R
A
V
Y
Rat
Rattus norvegicus
A6JUQ6
327
37898
S173
N
F
T
F
K
Q
A
S
K
L
T
P
S
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510973
445
49726
T149
V
P
S
R
Y
P
I
T
E
N
V
R
A
I
Y
Chicken
Gallus gallus
NP_001026025
300
33914
T157
T
P
S
H
Y
P
I
T
E
N
I
R
A
I
Y
Frog
Xenopus laevis
Q5M7E1
332
38511
S173
N
F
S
F
K
Q
A
S
K
L
T
P
S
I
L
Zebra Danio
Brachydanio rerio
Q5SPP0
329
38101
S173
N
F
T
F
K
Q
A
S
K
L
T
P
S
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03606
719
81064
W407
G
L
S
M
R
H
L
W
R
P
G
V
Q
C
L
Sea Urchin
Strong. purpuratus
XP_780795
286
33208
V145
F
M
V
I
D
Q
L
V
E
D
E
A
A
Q
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P33324
310
36055
K151
Q
M
L
R
N
L
V
K
E
Y
E
L
F
A
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.5
94.7
N.A.
94.1
33.3
N.A.
61.5
73.3
33.6
33.3
N.A.
N.A.
N.A.
20.4
31.5
Protein Similarity:
100
99.7
99.1
96.1
N.A.
98.2
49.4
N.A.
66.2
79.2
49.1
49.7
N.A.
N.A.
N.A.
30
50.2
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
80
86.6
13.3
0
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
93.3
93.3
33.3
33.3
N.A.
N.A.
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
24
0
0
0
0
8
62
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
70
0
16
0
0
0
0
% E
% Phe:
8
24
0
24
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
8
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
39
0
0
8
0
0
54
0
0
0
47
0
0
54
8
% I
% Lys:
0
0
0
0
24
0
0
8
24
0
0
0
0
0
0
% K
% Leu:
0
8
8
0
0
8
16
0
0
24
0
8
0
0
31
% L
% Met:
0
16
0
8
0
0
0
0
0
0
0
0
0
16
0
% M
% Asn:
24
0
0
39
8
0
0
0
0
54
0
0
0
0
0
% N
% Pro:
0
54
0
0
0
54
0
0
0
8
0
24
0
0
0
% P
% Gln:
8
0
0
0
0
31
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
16
8
0
0
0
8
0
0
54
0
0
0
% R
% Ser:
0
0
70
0
0
0
0
24
0
0
0
0
24
0
0
% S
% Thr:
8
0
16
0
0
0
0
54
0
0
24
0
0
0
8
% T
% Val:
8
0
8
0
0
0
8
8
0
0
8
8
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
54
0
0
0
0
8
0
0
0
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _