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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOHH
All Species:
51.21
Human Site:
S146
Identified Species:
75.11
UniProt:
Q9BU89
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BU89
NP_001138637.1
302
32904
S146
P
A
A
G
P
Y
L
S
V
D
P
A
P
P
A
Chimpanzee
Pan troglodytes
XP_512268
302
32823
S146
P
A
A
G
P
Y
L
S
V
D
P
A
P
P
A
Rhesus Macaque
Macaca mulatta
XP_001100385
302
32835
S146
P
T
A
G
P
Y
L
S
V
D
P
A
P
P
A
Dog
Lupus familis
XP_542178
303
33106
S148
V
A
A
G
P
Y
L
S
V
D
P
A
P
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99LN9
302
32887
S147
T
C
A
G
P
Y
L
S
V
D
P
A
P
P
A
Rat
Rattus norvegicus
Q5PPJ4
302
33058
S147
T
C
A
G
P
Y
L
S
V
D
P
A
P
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511251
308
33581
S146
P
G
V
N
P
Y
L
S
V
D
P
A
P
P
A
Chicken
Gallus gallus
Q5ZIP3
299
32857
S146
P
G
S
S
P
Y
R
S
V
D
P
A
P
P
A
Frog
Xenopus laevis
Q66KT3
303
33366
S148
P
D
T
N
P
Y
L
S
V
D
P
A
P
P
A
Zebra Danio
Brachydanio rerio
Q7ZUX6
305
33900
S150
T
D
E
N
P
Y
C
S
V
D
P
A
P
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9U4
302
33546
S146
D
D
S
N
P
Y
A
S
V
D
P
S
P
P
T
Honey Bee
Apis mellifera
XP_394239
303
34154
S150
L
Q
K
S
P
Y
M
S
V
D
P
A
P
P
T
Nematode Worm
Caenorhab. elegans
Q17949
298
33221
S150
D
T
N
S
P
Y
D
S
V
D
P
T
P
S
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94JW0
314
34074
S159
T
E
K
S
P
F
M
S
V
D
P
A
G
P
A
Baker's Yeast
Sacchar. cerevisiae
P47120
325
36146
S173
L
Q
Q
S
L
Y
S
S
I
D
P
A
P
P
L
Red Bread Mold
Neurospora crassa
Q7S891
324
35309
S157
L
R
Q
S
D
F
A
S
V
D
P
A
P
P
M
Conservation
Percent
Protein Identity:
100
97.3
97.6
87.4
N.A.
84.7
83.1
N.A.
77.2
74.5
68.9
65.9
N.A.
58.6
58.4
56.2
N.A.
Protein Similarity:
100
98
98.6
94.7
N.A.
92.3
90.4
N.A.
86.3
83.4
79.8
77.6
N.A.
73.5
72.6
70.5
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
80
73.3
80
66.6
N.A.
53.3
60
53.3
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
80
80
80
66.6
N.A.
66.6
66.6
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.4
46.4
45.3
Protein Similarity:
N.A.
N.A.
N.A.
61.4
59
60.1
P-Site Identity:
N.A.
N.A.
N.A.
53.3
46.6
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
53.3
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
38
0
0
0
13
0
0
0
0
88
0
0
75
% A
% Cys:
0
13
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
13
19
0
0
7
0
7
0
0
100
0
0
0
0
0
% D
% Glu:
0
7
7
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
13
0
38
0
0
0
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
19
0
0
0
7
0
50
0
0
0
0
0
0
0
7
% L
% Met:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
7
25
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
38
0
0
0
88
0
0
0
0
0
100
0
94
94
0
% P
% Gln:
0
13
13
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
13
38
0
0
7
100
0
0
0
7
0
7
0
% S
% Thr:
25
13
7
0
0
0
0
0
0
0
0
7
0
0
13
% T
% Val:
7
0
7
0
0
0
0
0
94
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
88
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _