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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DOHH
All Species:
44.55
Human Site:
S272
Identified Species:
65.33
UniProt:
Q9BU89
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BU89
NP_001138637.1
302
32904
S272
P
E
R
V
V
R
E
S
C
E
V
A
L
D
M
Chimpanzee
Pan troglodytes
XP_512268
302
32823
S272
P
E
R
V
V
R
E
S
C
E
V
A
L
D
M
Rhesus Macaque
Macaca mulatta
XP_001100385
302
32835
S272
P
E
R
V
V
R
E
S
C
E
V
A
L
D
M
Dog
Lupus familis
XP_542178
303
33106
S274
P
E
R
V
V
R
E
S
C
E
V
A
L
D
M
Cat
Felis silvestris
Mouse
Mus musculus
Q99LN9
302
32887
S273
P
E
Q
V
V
R
E
S
C
E
V
A
L
D
M
Rat
Rattus norvegicus
Q5PPJ4
302
33058
S273
P
E
R
V
V
R
E
S
C
E
V
A
L
D
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511251
308
33581
S272
T
E
R
V
V
R
E
S
C
E
V
A
L
D
M
Chicken
Gallus gallus
Q5ZIP3
299
32857
S253
L
G
S
I
A
R
P
S
C
L
E
T
L
R
A
Frog
Xenopus laevis
Q66KT3
303
33366
S274
G
E
R
V
V
R
E
S
C
E
V
A
L
D
M
Zebra Danio
Brachydanio rerio
Q7ZUX6
305
33900
S276
Q
E
R
V
V
K
E
S
C
E
V
A
L
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V9U4
302
33546
S273
D
K
R
V
V
K
E
S
C
V
I
A
L
D
M
Honey Bee
Apis mellifera
XP_394239
303
34154
D257
L
G
S
I
A
T
Q
D
C
F
D
I
L
N
K
Nematode Worm
Caenorhab. elegans
Q17949
298
33221
I262
A
N
E
E
C
T
E
I
L
K
Q
Y
V
N
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94JW0
314
34074
A264
A
E
A
L
G
S
I
A
D
E
Q
S
I
A
L
Baker's Yeast
Sacchar. cerevisiae
P47120
325
36146
V296
K
S
Y
L
N
D
E
V
D
V
V
R
E
S
C
Red Bread Mold
Neurospora crassa
Q7S891
324
35309
S295
K
E
K
V
V
R
E
S
V
I
V
A
L
D
M
Conservation
Percent
Protein Identity:
100
97.3
97.6
87.4
N.A.
84.7
83.1
N.A.
77.2
74.5
68.9
65.9
N.A.
58.6
58.4
56.2
N.A.
Protein Similarity:
100
98
98.6
94.7
N.A.
92.3
90.4
N.A.
86.3
83.4
79.8
77.6
N.A.
73.5
72.6
70.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
93.3
26.6
93.3
86.6
N.A.
66.6
13.3
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
33.3
93.3
93.3
N.A.
86.6
33.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.4
46.4
45.3
Protein Similarity:
N.A.
N.A.
N.A.
61.4
59
60.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
73.3
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
20
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
7
0
13
0
0
7
0
0
0
69
0
7
7
% A
% Cys:
0
0
0
0
7
0
0
0
75
0
0
0
0
0
7
% C
% Asp:
7
0
0
0
0
7
0
7
13
0
7
0
0
69
7
% D
% Glu:
0
69
7
7
0
0
82
0
0
63
7
0
7
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% F
% Gly:
7
13
0
0
7
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
13
0
0
7
7
0
7
7
7
7
0
0
% I
% Lys:
13
7
7
0
0
13
0
0
0
7
0
0
0
0
7
% K
% Leu:
13
0
0
13
0
0
0
0
7
7
0
0
82
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
69
% M
% Asn:
0
7
0
0
7
0
0
0
0
0
0
0
0
13
0
% N
% Pro:
38
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
7
0
0
0
7
0
0
0
13
0
0
0
0
% Q
% Arg:
0
0
57
0
0
63
0
0
0
0
0
7
0
7
0
% R
% Ser:
0
7
13
0
0
7
0
75
0
0
0
7
0
7
0
% S
% Thr:
7
0
0
0
0
13
0
0
0
0
0
7
0
0
0
% T
% Val:
0
0
0
69
69
0
0
7
7
13
69
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _