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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKNK1
All Species:
9.7
Human Site:
S15
Identified Species:
19.39
UniProt:
Q9BUB5
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUB5
NP_001129025.1
465
51342
S15
E
K
P
I
E
M
G
S
S
E
P
L
P
I
A
Chimpanzee
Pan troglodytes
XP_001162271
453
49967
R15
P
I
A
D
G
V
R
R
R
K
K
K
R
R
A
Rhesus Macaque
Macaca mulatta
XP_001098645
414
46209
Dog
Lupus familis
XP_539626
415
46182
Cat
Felis silvestris
Mouse
Mus musculus
O08605
427
47896
S15
E
K
P
I
E
M
G
S
S
E
P
L
P
I
V
Rat
Rattus norvegicus
Q4G050
413
46195
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235171
508
56331
P15
L
R
A
C
A
L
P
P
S
P
A
G
G
L
S
Frog
Xenopus laevis
Q9YGW0
418
46898
D10
S
S
Q
P
V
P
F
D
D
G
G
K
R
R
K
Zebra Danio
Brachydanio rerio
NP_001108211
459
51123
S15
Q
R
D
S
F
G
C
S
L
Q
L
A
P
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651986
1142
128445
S73
E
D
V
S
G
N
E
S
S
E
A
P
N
M
T
Honey Bee
Apis mellifera
XP_395927
516
58135
N16
A
N
C
R
D
T
V
N
S
T
G
E
S
M
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779905
511
56921
T28
T
P
I
T
K
M
P
T
G
D
K
M
T
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
87.9
82.8
N.A.
85.3
82.3
N.A.
N.A.
51.5
72
68.3
N.A.
20.3
46.1
N.A.
37.7
Protein Similarity:
100
96.7
88.1
85.8
N.A.
88.5
85.3
N.A.
N.A.
63.3
79.7
76.7
N.A.
28.2
63.1
N.A.
52.4
P-Site Identity:
100
6.6
0
0
N.A.
93.3
0
N.A.
N.A.
6.6
0
13.3
N.A.
26.6
6.6
N.A.
6.6
P-Site Similarity:
100
20
0
0
N.A.
93.3
0
N.A.
N.A.
33.3
0
40
N.A.
33.3
33.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
17
0
9
0
0
0
0
0
17
9
0
0
17
% A
% Cys:
0
0
9
9
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
9
9
0
0
9
9
9
0
0
0
0
0
% D
% Glu:
25
0
0
0
17
0
9
0
0
25
0
9
0
0
0
% E
% Phe:
0
0
0
0
9
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
17
9
17
0
9
9
17
9
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
9
17
0
0
0
0
0
0
0
0
0
17
0
% I
% Lys:
0
17
0
0
9
0
0
0
0
9
17
17
0
0
9
% K
% Leu:
9
0
0
0
0
9
0
0
9
0
9
17
0
17
9
% L
% Met:
0
0
0
0
0
25
0
0
0
0
0
9
0
17
0
% M
% Asn:
0
9
0
0
0
9
0
9
0
0
0
0
9
0
0
% N
% Pro:
9
9
17
9
0
9
17
9
0
9
17
9
25
0
0
% P
% Gln:
9
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
17
0
9
0
0
9
9
9
0
0
0
17
17
0
% R
% Ser:
9
9
0
17
0
0
0
34
42
0
0
0
9
0
25
% S
% Thr:
9
0
0
9
0
9
0
9
0
9
0
0
9
0
9
% T
% Val:
0
0
9
0
9
9
9
0
0
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _