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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MKNK1 All Species: 8.79
Human Site: S16 Identified Species: 17.58
UniProt: Q9BUB5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BUB5 NP_001129025.1 465 51342 S16 K P I E M G S S E P L P I A D
Chimpanzee Pan troglodytes XP_001162271 453 49967 R16 I A D G V R R R K K K R R A R
Rhesus Macaque Macaca mulatta XP_001098645 414 46209
Dog Lupus familis XP_539626 415 46182 P8 M G S S E P L P I A E G D K R
Cat Felis silvestris
Mouse Mus musculus O08605 427 47896 S16 K P I E M G S S E P L P I V D
Rat Rattus norvegicus Q4G050 413 46195
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001235171 508 56331 S16 R A C A L P P S P A G G L S G
Frog Xenopus laevis Q9YGW0 418 46898 D11 S Q P V P F D D G G K R R K K
Zebra Danio Brachydanio rerio NP_001108211 459 51123 L16 R D S F G C S L Q L A P L L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651986 1142 128445 S74 D V S G N E S S E A P N M T E
Honey Bee Apis mellifera XP_395927 516 58135 S17 N C R D T V N S T G E S M S A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_779905 511 56921 G29 P I T K M P T G D K M T V S Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.7 87.9 82.8 N.A. 85.3 82.3 N.A. N.A. 51.5 72 68.3 N.A. 20.3 46.1 N.A. 37.7
Protein Similarity: 100 96.7 88.1 85.8 N.A. 88.5 85.3 N.A. N.A. 63.3 79.7 76.7 N.A. 28.2 63.1 N.A. 52.4
P-Site Identity: 100 6.6 0 0 N.A. 93.3 0 N.A. N.A. 6.6 0 13.3 N.A. 20 6.6 N.A. 6.6
P-Site Similarity: 100 20 0 0 N.A. 93.3 0 N.A. N.A. 33.3 0 33.3 N.A. 33.3 33.3 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 9 0 0 0 0 0 25 9 0 0 17 9 % A
% Cys: 0 9 9 0 0 9 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 9 9 9 0 0 9 9 9 0 0 0 9 0 17 % D
% Glu: 0 0 0 17 9 9 0 0 25 0 17 0 0 0 9 % E
% Phe: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 17 9 17 0 9 9 17 9 17 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 9 17 0 0 0 0 0 9 0 0 0 17 0 0 % I
% Lys: 17 0 0 9 0 0 0 0 9 17 17 0 0 17 9 % K
% Leu: 0 0 0 0 9 0 9 9 0 9 17 0 17 9 0 % L
% Met: 9 0 0 0 25 0 0 0 0 0 9 0 17 0 0 % M
% Asn: 9 0 0 0 9 0 9 0 0 0 0 9 0 0 0 % N
% Pro: 9 17 9 0 9 25 9 9 9 17 9 25 0 0 0 % P
% Gln: 0 9 0 0 0 0 0 0 9 0 0 0 0 0 17 % Q
% Arg: 17 0 9 0 0 9 9 9 0 0 0 17 17 0 17 % R
% Ser: 9 0 25 9 0 0 34 42 0 0 0 9 0 25 0 % S
% Thr: 0 0 9 0 9 0 9 0 9 0 0 9 0 9 0 % T
% Val: 0 9 0 9 9 9 0 0 0 0 0 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _