KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MKNK1
All Species:
14.24
Human Site:
T246
Identified Species:
28.48
UniProt:
Q9BUB5
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUB5
NP_001129025.1
465
51342
T246
M
K
L
N
N
S
C
T
P
I
T
T
P
E
L
Chimpanzee
Pan troglodytes
XP_001162271
453
49967
T234
M
K
L
N
N
S
C
T
P
I
T
T
P
E
L
Rhesus Macaque
Macaca mulatta
XP_001098645
414
46209
F224
V
F
T
D
Q
A
T
F
Y
D
K
R
C
D
L
Dog
Lupus familis
XP_539626
415
46182
Y225
F
R
D
E
A
T
F
Y
D
K
R
C
D
L
W
Cat
Felis silvestris
Mouse
Mus musculus
O08605
427
47896
A234
V
E
V
F
R
D
E
A
T
F
Y
D
K
R
C
Rat
Rattus norvegicus
Q4G050
413
46195
A222
V
E
V
F
R
D
E
A
T
F
Y
D
K
R
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235171
508
56331
T288
V
K
L
N
S
A
C
T
P
I
T
T
P
E
L
Frog
Xenopus laevis
Q9YGW0
418
46898
R228
E
A
T
F
Y
D
K
R
C
D
L
W
S
L
G
Zebra Danio
Brachydanio rerio
NP_001108211
459
51123
T252
V
K
L
N
S
A
C
T
P
I
T
T
P
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651986
1142
128445
N431
T
P
S
N
I
R
R
N
H
Q
S
A
R
E
I
Honey Bee
Apis mellifera
XP_395927
516
58135
G273
P
P
F
Y
G
N
C
G
S
D
C
G
W
E
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779905
511
56921
L312
V
Y
D
K
R
C
D
L
W
S
L
G
V
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.7
87.9
82.8
N.A.
85.3
82.3
N.A.
N.A.
51.5
72
68.3
N.A.
20.3
46.1
N.A.
37.7
Protein Similarity:
100
96.7
88.1
85.8
N.A.
88.5
85.3
N.A.
N.A.
63.3
79.7
76.7
N.A.
28.2
63.1
N.A.
52.4
P-Site Identity:
100
100
6.6
0
N.A.
0
0
N.A.
N.A.
80
0
80
N.A.
13.3
13.3
N.A.
6.6
P-Site Similarity:
100
100
33.3
13.3
N.A.
20
20
N.A.
N.A.
100
0
100
N.A.
26.6
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
25
0
17
0
0
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
9
42
0
9
0
9
9
9
0
17
% C
% Asp:
0
0
17
9
0
25
9
0
9
25
0
17
9
9
0
% D
% Glu:
9
17
0
9
0
0
17
0
0
0
0
0
0
50
0
% E
% Phe:
9
9
9
25
0
0
9
9
0
17
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
9
0
0
0
17
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
34
0
0
0
9
9
% I
% Lys:
0
34
0
9
0
0
9
0
0
9
9
0
17
0
0
% K
% Leu:
0
0
34
0
0
0
0
9
0
0
17
0
0
17
50
% L
% Met:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
42
17
9
0
9
0
0
0
0
0
0
0
% N
% Pro:
9
17
0
0
0
0
0
0
34
0
0
0
34
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
9
0
0
25
9
9
9
0
0
9
9
9
17
9
% R
% Ser:
0
0
9
0
17
17
0
0
9
9
9
0
9
0
0
% S
% Thr:
9
0
17
0
0
9
9
34
17
0
34
34
0
0
0
% T
% Val:
50
0
17
0
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
9
9
0
9
% W
% Tyr:
0
9
0
9
9
0
0
9
9
0
17
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _