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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED18
All Species:
27.27
Human Site:
S66
Identified Species:
54.55
UniProt:
Q9BUE0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUE0
NP_001120822.1
208
23663
S66
L
L
K
G
Q
Q
A
S
P
F
V
L
R
A
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113062
208
23612
S66
L
L
K
G
Q
Q
A
S
P
F
V
L
R
A
R
Dog
Lupus familis
XP_544460
208
23658
S66
L
L
K
G
Q
Q
A
S
P
F
V
L
R
A
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZ82
208
23626
S66
L
L
K
G
Q
Q
A
S
P
F
V
L
R
A
R
Rat
Rattus norvegicus
NP_001108509
208
23640
S66
L
L
K
G
Q
Q
A
S
P
F
V
L
R
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509575
208
23346
S66
L
L
K
G
Q
Q
A
S
P
F
V
L
R
A
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DD39
208
23191
S66
L
L
K
G
Q
Q
A
S
P
F
V
L
R
A
R
Zebra Danio
Brachydanio rerio
Q7T3H7
208
23270
N66
L
L
K
G
Q
Q
G
N
P
F
I
L
R
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9XZT1
217
24654
N72
S
L
R
Q
P
N
A
N
Q
P
L
L
L
R
V
Honey Bee
Apis mellifera
XP_392263
216
24397
Q72
F
S
I
R
G
S
E
Q
P
L
L
L
R
V
R
Nematode Worm
Caenorhab. elegans
Q966M5
232
26608
D77
G
I
M
D
I
K
T
D
I
K
L
R
R
R
F
Sea Urchin
Strong. purpuratus
XP_781912
203
22653
Q71
F
I
L
R
G
Q
N
Q
Q
A
M
L
R
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
99
N.A.
98.5
99
N.A.
89.9
N.A.
78.3
80.7
N.A.
50.2
55
28.8
48.5
Protein Similarity:
100
N.A.
100
99.5
N.A.
100
100
N.A.
95.1
N.A.
88.9
91.8
N.A.
68.6
73.1
49.5
68.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
100
80
N.A.
20
26.6
6.6
33.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
N.A.
100
93.3
N.A.
40
33.3
26.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
67
0
0
9
0
0
0
75
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
17
0
0
0
0
0
0
0
0
67
0
0
0
0
9
% F
% Gly:
9
0
0
67
17
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
17
9
0
9
0
0
0
9
0
9
0
0
0
0
% I
% Lys:
0
0
67
0
0
9
0
0
0
9
0
0
0
0
0
% K
% Leu:
67
75
9
0
0
0
0
0
0
9
25
92
9
0
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
9
9
17
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
0
0
75
9
0
0
0
0
0
% P
% Gln:
0
0
0
9
67
75
0
17
17
0
0
0
0
0
0
% Q
% Arg:
0
0
9
17
0
0
0
0
0
0
0
9
92
17
84
% R
% Ser:
9
9
0
0
0
9
0
59
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
59
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _