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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISCA1
All Species:
29.09
Human Site:
S73
Identified Species:
45.71
UniProt:
Q9BUE6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUE6
NP_112202.2
129
14179
S73
Y
T
K
T
K
G
D
S
D
E
E
V
I
Q
D
Chimpanzee
Pan troglodytes
XP_001134901
163
18042
S73
Y
T
K
T
K
G
D
S
D
K
E
F
I
Q
D
Rhesus Macaque
Macaca mulatta
XP_001082763
131
14597
S76
Y
T
K
I
K
G
D
S
D
E
V
I
Q
D
G
Dog
Lupus familis
XP_849435
260
28207
S204
Y
T
K
T
K
G
D
S
D
E
E
V
V
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D924
129
14170
S73
Y
T
K
T
K
G
D
S
D
E
E
V
I
Q
D
Rat
Rattus norvegicus
Q80W96
129
14131
A73
Y
T
K
T
K
G
D
A
D
E
E
V
I
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511499
129
14098
S73
Y
T
K
T
K
G
D
S
D
E
E
V
V
Q
D
Chicken
Gallus gallus
Q5ZJ74
129
14107
S73
Y
T
K
S
K
G
D
S
D
E
E
V
V
Q
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q4QRC6
129
14230
S73
Y
T
K
N
K
E
Q
S
D
E
E
V
L
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573062
130
14122
L74
Y
A
S
Q
K
D
K
L
D
E
E
V
V
Q
D
Honey Bee
Apis mellifera
XP_624993
130
14123
L74
Y
A
K
E
K
S
K
L
D
E
E
V
V
Q
D
Nematode Worm
Caenorhab. elegans
NP_741696
129
14172
F73
Y
A
K
D
K
Q
K
F
D
E
E
V
E
Q
D
Sea Urchin
Strong. purpuratus
XP_798918
129
14079
F73
Y
A
K
E
K
Q
K
F
D
E
E
V
V
Q
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LBM4
137
14967
F70
Y
A
D
E
K
G
K
F
D
E
L
V
E
E
K
Baker's Yeast
Sacchar. cerevisiae
Q07821
250
27656
F194
Y
I
T
E
P
G
K
F
D
E
V
V
E
Q
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.4
86.2
48.8
N.A.
96.9
96.9
N.A.
96.1
93
N.A.
84.5
N.A.
74.6
71.5
62
71.3
Protein Similarity:
100
76.6
91.5
49.6
N.A.
100
100
N.A.
99.2
98.4
N.A.
93.8
N.A.
86.1
85.3
76.7
83.7
P-Site Identity:
100
86.6
60
93.3
N.A.
100
93.3
N.A.
93.3
86.6
N.A.
73.3
N.A.
53.3
60
60
60
P-Site Similarity:
100
93.3
66.6
100
N.A.
100
100
N.A.
100
100
N.A.
80
N.A.
60
66.6
60
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.5
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62
39.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
0
0
0
7
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
7
0
7
54
0
100
0
0
0
0
7
87
% D
% Glu:
0
0
0
27
0
7
0
0
0
94
80
0
20
7
0
% E
% Phe:
0
0
0
0
0
0
0
27
0
0
0
7
0
0
0
% F
% Gly:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
7
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
7
0
0
0
0
0
0
0
7
27
0
0
% I
% Lys:
0
0
80
0
94
0
40
0
0
7
0
0
0
0
7
% K
% Leu:
0
0
0
0
0
0
0
14
0
0
7
0
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
0
14
7
0
0
0
0
0
7
87
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
7
0
7
0
54
0
0
0
0
0
0
0
% S
% Thr:
0
60
7
40
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
14
87
40
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _