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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ISCA1
All Species:
57.58
Human Site:
Y62
Identified Species:
90.48
UniProt:
Q9BUE6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUE6
NP_112202.2
129
14179
Y62
R
G
C
N
G
L
S
Y
T
L
E
Y
T
K
T
Chimpanzee
Pan troglodytes
XP_001134901
163
18042
Y62
R
G
C
N
G
L
S
Y
T
L
E
Y
T
K
T
Rhesus Macaque
Macaca mulatta
XP_001082763
131
14597
Y65
R
G
S
N
G
L
S
Y
T
L
E
Y
T
K
I
Dog
Lupus familis
XP_849435
260
28207
Y193
R
G
C
N
G
L
S
Y
T
L
E
Y
T
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D924
129
14170
Y62
R
G
C
N
G
L
S
Y
S
L
E
Y
T
K
T
Rat
Rattus norvegicus
Q80W96
129
14131
Y62
R
G
C
N
G
L
S
Y
S
L
E
Y
T
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511499
129
14098
Y62
R
G
C
N
G
L
S
Y
T
L
E
Y
T
K
T
Chicken
Gallus gallus
Q5ZJ74
129
14107
Y62
R
G
C
N
G
L
S
Y
T
L
E
Y
T
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q4QRC6
129
14230
Y62
R
G
C
N
G
L
T
Y
T
L
D
Y
T
K
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573062
130
14122
Y63
R
G
C
N
G
L
S
Y
T
L
D
Y
A
S
Q
Honey Bee
Apis mellifera
XP_624993
130
14123
Y63
R
G
C
N
G
L
S
Y
T
L
D
Y
A
K
E
Nematode Worm
Caenorhab. elegans
NP_741696
129
14172
Y62
K
G
C
N
G
L
T
Y
T
L
E
Y
A
K
D
Sea Urchin
Strong. purpuratus
XP_798918
129
14079
Y62
R
G
C
N
G
L
S
Y
T
L
D
Y
A
K
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LBM4
137
14967
Y59
R
G
C
N
G
L
S
Y
T
L
N
Y
A
D
E
Baker's Yeast
Sacchar. cerevisiae
Q07821
250
27656
Y183
R
G
C
S
G
L
T
Y
D
L
Q
Y
I
T
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.4
86.2
48.8
N.A.
96.9
96.9
N.A.
96.1
93
N.A.
84.5
N.A.
74.6
71.5
62
71.3
Protein Similarity:
100
76.6
91.5
49.6
N.A.
100
100
N.A.
99.2
98.4
N.A.
93.8
N.A.
86.1
85.3
76.7
83.7
P-Site Identity:
100
100
86.6
100
N.A.
93.3
93.3
N.A.
100
93.3
N.A.
80
N.A.
73.3
80
73.3
80
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
100
100
N.A.
93.3
N.A.
80
86.6
86.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.5
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62
39.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
34
0
0
% A
% Cys:
0
0
94
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
7
0
27
0
0
7
7
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
60
0
0
0
27
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
100
0
0
100
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% I
% Lys:
7
0
0
0
0
0
0
0
0
0
0
0
0
80
0
% K
% Leu:
0
0
0
0
0
100
0
0
0
100
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
94
0
0
0
0
0
0
7
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
7
% Q
% Arg:
94
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
7
7
0
0
80
0
14
0
0
0
0
7
7
% S
% Thr:
0
0
0
0
0
0
20
0
80
0
0
0
60
7
40
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
100
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _