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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3C All Species: 17.58
Human Site: S169 Identified Species: 35.15
UniProt: Q9BUI4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BUI4 NP_006459.3 534 60612 S169 S V P T T E N S D P G P P P P
Chimpanzee Pan troglodytes XP_001161518 508 57536 S169 S V P T T E N S D P G P P P P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540277 534 60596 S169 W V P A T E N S D P G P L P P
Cat Felis silvestris
Mouse Mus musculus Q9D483 533 60687 S169 L V P D T D S S D R G P P P P
Rat Rattus norvegicus Q5XIL3 533 60524 S169 L V P D T D S S D P G P P P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519209 341 37130
Chicken Gallus gallus
Frog Xenopus laevis NP_001086474 529 60253 A168 P G L Q E K D A T E G R P P L
Zebra Danio Brachydanio rerio Q7ZUX1 539 60470 S172 P M A S A E S S G T G S A E T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650207 522 59801 D167 L L V G D D Q D E N V P K F E
Honey Bee Apis mellifera XP_394638 432 50172 L93 R M E Q S P Y L D L A A I S K
Nematode Worm Caenorhab. elegans NP_491807 544 61746 N172 G C P Q F V T N F D P F A I S
Sea Urchin Strong. purpuratus XP_001190037 532 61023 E169 W S A E D D E E S K V I P L I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.7 N.A. 96.2 N.A. 93.8 93.8 N.A. 42.8 N.A. 77.7 65.6 N.A. 33.9 34.4 23.1 49.2
Protein Similarity: 100 95.1 N.A. 97.7 N.A. 96.6 96.6 N.A. 49.6 N.A. 88.5 79.9 N.A. 54.3 53.9 47.6 71.3
P-Site Identity: 100 100 N.A. 80 N.A. 66.6 73.3 N.A. 0 N.A. 20 20 N.A. 6.6 6.6 6.6 6.6
P-Site Similarity: 100 100 N.A. 80 N.A. 80 86.6 N.A. 0 N.A. 40 40 N.A. 26.6 20 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 9 9 0 0 9 0 0 9 9 17 0 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 17 17 34 9 9 50 9 0 0 0 0 0 % D
% Glu: 0 0 9 9 9 34 9 9 9 9 0 0 0 9 9 % E
% Phe: 0 0 0 0 9 0 0 0 9 0 0 9 0 9 0 % F
% Gly: 9 9 0 9 0 0 0 0 9 0 59 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 9 9 9 9 % I
% Lys: 0 0 0 0 0 9 0 0 0 9 0 0 9 0 9 % K
% Leu: 25 9 9 0 0 0 0 9 0 9 0 0 9 9 9 % L
% Met: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 25 9 0 9 0 0 0 0 0 % N
% Pro: 17 0 50 0 0 9 0 0 0 34 9 50 50 50 42 % P
% Gln: 0 0 0 25 0 0 9 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 9 0 9 0 0 0 % R
% Ser: 17 9 0 9 9 0 25 50 9 0 0 9 0 9 9 % S
% Thr: 0 0 0 17 42 0 9 0 9 9 0 0 0 0 9 % T
% Val: 0 42 9 0 0 9 0 0 0 0 17 0 0 0 0 % V
% Trp: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _