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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3C
All Species:
19.39
Human Site:
S296
Identified Species:
38.79
UniProt:
Q9BUI4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUI4
NP_006459.3
534
60612
S296
S
S
N
E
I
F
R
S
L
P
V
G
Y
N
I
Chimpanzee
Pan troglodytes
XP_001161518
508
57536
E292
T
Q
P
L
S
S
N
E
I
F
R
S
L
P
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540277
534
60596
S296
S
S
N
E
I
F
R
S
L
P
V
G
Y
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9D483
533
60687
S295
S
S
N
E
I
F
R
S
L
P
V
G
Y
N
I
Rat
Rattus norvegicus
Q5XIL3
533
60524
S295
S
S
N
E
I
F
R
S
L
P
V
G
Y
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519209
341
37130
P125
P
E
R
E
A
A
W
P
D
G
K
T
V
D
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086474
529
60253
S291
S
S
N
E
I
F
R
S
L
P
T
G
Y
N
V
Zebra Danio
Brachydanio rerio
Q7ZUX1
539
60470
A301
S
A
N
E
I
F
R
A
L
P
S
N
Y
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650207
522
59801
T295
D
Q
Y
I
S
L
L
T
E
D
S
L
G
F
F
Honey Bee
Apis mellifera
XP_394638
432
50172
S216
D
S
G
G
G
Q
Y
S
V
N
M
K
E
A
F
Nematode Worm
Caenorhab. elegans
NP_491807
544
61746
V302
L
T
D
L
Q
R
L
V
K
E
N
G
L
N
L
Sea Urchin
Strong. purpuratus
XP_001190037
532
61023
A293
P
L
S
F
H
D
I
A
R
Q
M
P
K
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.7
N.A.
96.2
N.A.
93.8
93.8
N.A.
42.8
N.A.
77.7
65.6
N.A.
33.9
34.4
23.1
49.2
Protein Similarity:
100
95.1
N.A.
97.7
N.A.
96.6
96.6
N.A.
49.6
N.A.
88.5
79.9
N.A.
54.3
53.9
47.6
71.3
P-Site Identity:
100
0
N.A.
100
N.A.
100
100
N.A.
6.6
N.A.
86.6
73.3
N.A.
0
13.3
13.3
0
P-Site Similarity:
100
20
N.A.
100
N.A.
100
100
N.A.
13.3
N.A.
93.3
86.6
N.A.
6.6
26.6
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
9
0
17
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
9
0
0
9
0
0
9
9
0
0
0
9
0
% D
% Glu:
0
9
0
59
0
0
0
9
9
9
0
0
9
0
0
% E
% Phe:
0
0
0
9
0
50
0
0
0
9
0
0
0
9
17
% F
% Gly:
0
0
9
9
9
0
0
0
0
9
0
50
9
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
50
0
9
0
9
0
0
0
0
0
42
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
9
9
9
9
0
% K
% Leu:
9
9
0
17
0
9
17
0
50
0
0
9
17
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% M
% Asn:
0
0
50
0
0
0
9
0
0
9
9
9
0
59
0
% N
% Pro:
17
0
9
0
0
0
0
9
0
50
0
9
0
9
0
% P
% Gln:
0
17
0
0
9
9
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
0
9
0
0
9
50
0
9
0
9
0
0
0
0
% R
% Ser:
50
50
9
0
17
9
0
50
0
0
17
9
0
0
0
% S
% Thr:
9
9
0
0
0
0
0
9
0
0
9
9
0
0
0
% T
% Val:
0
0
0
0
0
0
0
9
9
0
34
0
9
0
17
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
9
0
0
0
0
0
50
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _