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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: POLR3C All Species: 28.18
Human Site: T492 Identified Species: 56.36
UniProt: Q9BUI4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BUI4 NP_006459.3 534 60612 T492 Q E I E E M I T A P E R Q Q L
Chimpanzee Pan troglodytes XP_001161518 508 57536 V467 L L E K S Q R V E A I I A S M
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540277 534 60596 T492 Q E I E E M I T V P E R Q Q L
Cat Felis silvestris
Mouse Mus musculus Q9D483 533 60687 T491 Q E I E E M I T A P E R Q Q L
Rat Rattus norvegicus Q5XIL3 533 60524 T491 Q E I E E M I T A P E R Q Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519209 341 37130 A300 D Q Y L T L L A D D P L E F V
Chicken Gallus gallus
Frog Xenopus laevis NP_001086474 529 60253 T487 Q E I E E M I T A P E R Q Q L
Zebra Danio Brachydanio rerio Q7ZUX1 539 60470 T497 T E V E E M I T A P E R Q Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650207 522 59801 T473 A E I V E T F T P P E C E I L
Honey Bee Apis mellifera XP_394638 432 50172 L391 V Q N T I K K L G I T E L Q I
Nematode Worm Caenorhab. elegans NP_491807 544 61746 V498 K L A Q I A E V E E M Y L P G
Sea Urchin Strong. purpuratus XP_001190037 532 61023 T489 E E I E K T M T Q L E K E Q L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.7 N.A. 96.2 N.A. 93.8 93.8 N.A. 42.8 N.A. 77.7 65.6 N.A. 33.9 34.4 23.1 49.2
Protein Similarity: 100 95.1 N.A. 97.7 N.A. 96.6 96.6 N.A. 49.6 N.A. 88.5 79.9 N.A. 54.3 53.9 47.6 71.3
P-Site Identity: 100 0 N.A. 93.3 N.A. 100 100 N.A. 0 N.A. 100 86.6 N.A. 46.6 6.6 0 46.6
P-Site Similarity: 100 13.3 N.A. 93.3 N.A. 100 100 N.A. 33.3 N.A. 100 93.3 N.A. 53.3 20 13.3 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 0 9 0 9 42 9 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % D
% Glu: 9 67 9 59 59 0 9 0 17 9 67 9 25 0 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 59 0 17 0 50 0 0 9 9 9 0 9 9 % I
% Lys: 9 0 0 9 9 9 9 0 0 0 0 9 0 0 0 % K
% Leu: 9 17 0 9 0 9 9 9 0 9 0 9 17 0 67 % L
% Met: 0 0 0 0 0 50 9 0 0 0 9 0 0 0 9 % M
% Asn: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 9 59 9 0 0 9 0 % P
% Gln: 42 17 0 9 0 9 0 0 9 0 0 0 50 67 0 % Q
% Arg: 0 0 0 0 0 0 9 0 0 0 0 50 0 0 0 % R
% Ser: 0 0 0 0 9 0 0 0 0 0 0 0 0 9 0 % S
% Thr: 9 0 0 9 9 17 0 67 0 0 9 0 0 0 0 % T
% Val: 9 0 9 9 0 0 0 17 9 0 0 0 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _