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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHF23
All Species:
20.61
Human Site:
S218
Identified Species:
45.33
UniProt:
Q9BUL5
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUL5
NP_077273.2
403
43818
S218
K
R
S
R
I
K
K
S
K
K
R
K
L
K
K
Chimpanzee
Pan troglodytes
XP_001169367
403
43830
S218
K
R
S
R
I
K
K
S
K
K
R
K
L
K
K
Rhesus Macaque
Macaca mulatta
XP_001106687
403
43802
S218
K
R
S
R
I
K
K
S
K
K
R
K
L
K
K
Dog
Lupus familis
XP_848850
399
43241
S214
K
R
S
R
I
K
K
S
K
K
R
K
L
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSN5
401
43528
S217
K
R
S
R
I
K
K
S
K
K
R
K
L
K
K
Rat
Rattus norvegicus
Q6AY75
334
36213
P167
D
R
L
P
P
P
G
P
P
R
A
P
P
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519103
331
36738
E164
D
A
E
A
P
V
A
E
E
Y
M
G
S
L
L
Chicken
Gallus gallus
XP_425732
284
31676
E116
R
E
T
E
V
S
A
E
E
D
Y
E
E
K
L
Frog
Xenopus laevis
Q0IHB0
269
29110
T102
S
D
I
S
T
I
E
T
F
V
M
K
A
K
S
Zebra Danio
Brachydanio rerio
Q5BJ10
296
33413
S129
D
S
L
N
H
V
H
S
K
A
E
R
K
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785537
187
21302
P20
R
V
S
I
M
K
K
P
K
T
E
K
E
D
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.5
94.2
N.A.
94
77.6
N.A.
27.7
28.7
39.9
36.2
N.A.
N.A.
N.A.
N.A.
24.3
Protein Similarity:
100
99.7
99.5
95.5
N.A.
95.5
78.9
N.A.
40.2
39.9
49.6
46.4
N.A.
N.A.
N.A.
N.A.
32.5
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
0
6.6
13.3
20
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
6.6
40
26.6
26.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
19
0
0
10
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
28
10
0
0
0
0
0
0
0
10
0
0
0
10
10
% D
% Glu:
0
10
10
10
0
0
10
19
19
0
19
10
19
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
10
10
46
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
46
0
0
0
0
55
55
0
64
46
0
64
10
73
46
% K
% Leu:
0
0
19
0
0
0
0
0
0
0
0
0
46
10
19
% L
% Met:
0
0
0
0
10
0
0
0
0
0
19
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
19
10
0
19
10
0
0
10
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
19
55
0
46
0
0
0
0
0
10
46
10
0
0
0
% R
% Ser:
10
10
55
10
0
10
0
55
0
0
0
0
10
10
10
% S
% Thr:
0
0
10
0
10
0
0
10
0
10
0
0
0
0
0
% T
% Val:
0
10
0
0
10
19
0
0
0
10
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _