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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPP25
All Species:
15.15
Human Site:
S186
Identified Species:
33.33
UniProt:
Q9BUL9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUL9
NP_060263.2
199
20632
S186
G
E
G
S
A
K
R
S
Q
P
E
P
G
V
A
Chimpanzee
Pan troglodytes
XP_510676
199
20600
S186
G
E
G
S
A
K
R
S
Q
P
E
P
G
A
T
Rhesus Macaque
Macaca mulatta
XP_001101885
199
20634
S186
G
E
G
S
A
K
R
S
Q
P
E
P
G
A
A
Dog
Lupus familis
XP_854362
213
22209
L200
A
E
G
S
A
K
R
L
R
P
E
P
G
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q91WE3
199
21019
S186
E
E
G
T
A
K
R
S
Q
P
E
P
E
A
E
Rat
Rattus norvegicus
Q5PPN2
199
20920
S186
G
E
G
T
A
K
R
S
Q
P
E
P
E
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518454
201
21546
A189
A
E
R
T
G
L
A
A
L
P
L
R
R
G
P
Chicken
Gallus gallus
XP_428398
193
21140
P179
Q
V
A
G
A
S
S
P
Q
G
S
G
T
R
D
Frog
Xenopus laevis
NP_001087536
186
20922
R174
G
E
G
R
R
Q
S
R
G
T
G
G
R
G
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724490
206
23128
R182
R
G
G
R
P
N
K
R
T
R
P
G
R
N
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798043
237
27106
R180
S
A
R
S
V
N
Q
R
Q
D
R
D
G
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
96.4
81.6
N.A.
87.9
88.4
N.A.
38.3
49.2
38.6
N.A.
N.A.
29.6
N.A.
N.A.
28.6
Protein Similarity:
100
97.9
96.9
84
N.A.
90.4
90.9
N.A.
49.7
61.8
53.2
N.A.
N.A.
44.1
N.A.
N.A.
40
P-Site Identity:
100
86.6
93.3
73.3
N.A.
66.6
73.3
N.A.
13.3
13.3
20
N.A.
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
86.6
93.3
80
N.A.
73.3
80
N.A.
26.6
13.3
26.6
N.A.
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
10
0
64
0
10
10
0
0
0
0
0
37
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
10
% D
% Glu:
10
73
0
0
0
0
0
0
0
0
55
0
19
0
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
46
10
73
10
10
0
0
0
10
10
10
28
46
19
19
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
55
10
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
0
10
0
10
10
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
19
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
10
0
0
10
0
64
10
55
0
0
10
% P
% Gln:
10
0
0
0
0
10
10
0
64
0
0
0
0
10
0
% Q
% Arg:
10
0
19
19
10
0
55
28
10
10
10
10
28
10
0
% R
% Ser:
10
0
0
46
0
10
19
46
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
28
0
0
0
0
10
10
0
0
10
10
10
% T
% Val:
0
10
0
0
10
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _