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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPP25
All Species:
28.48
Human Site:
S68
Identified Species:
62.67
UniProt:
Q9BUL9
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUL9
NP_060263.2
199
20632
S68
A
T
R
A
I
V
F
S
G
C
G
R
A
T
T
Chimpanzee
Pan troglodytes
XP_510676
199
20600
S68
A
T
R
A
I
V
F
S
G
C
G
R
A
T
T
Rhesus Macaque
Macaca mulatta
XP_001101885
199
20634
S68
A
T
R
A
I
V
F
S
G
C
G
R
A
T
T
Dog
Lupus familis
XP_854362
213
22209
S82
A
T
R
A
I
V
F
S
G
C
G
R
A
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q91WE3
199
21019
S68
A
T
R
A
I
V
F
S
G
C
G
R
A
T
T
Rat
Rattus norvegicus
Q5PPN2
199
20920
S68
A
T
R
A
I
V
F
S
G
C
G
R
A
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518454
201
21546
T69
R
A
V
G
K
T
V
T
C
V
E
I
A
K
R
Chicken
Gallus gallus
XP_428398
193
21140
R62
I
V
F
S
G
C
G
R
A
V
T
K
T
I
T
Frog
Xenopus laevis
NP_001087536
186
20922
F57
E
S
V
R
Q
M
L
F
V
G
S
G
R
A
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724490
206
23128
S65
E
H
R
C
V
V
W
S
G
S
G
G
G
V
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798043
237
27106
T62
G
N
R
S
I
I
F
T
G
T
G
T
A
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
96.4
81.6
N.A.
87.9
88.4
N.A.
38.3
49.2
38.6
N.A.
N.A.
29.6
N.A.
N.A.
28.6
Protein Similarity:
100
97.9
96.9
84
N.A.
90.4
90.9
N.A.
49.7
61.8
53.2
N.A.
N.A.
44.1
N.A.
N.A.
40
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
6.6
0
N.A.
N.A.
33.3
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
20
13.3
N.A.
N.A.
46.6
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
55
10
0
55
0
0
0
0
10
0
0
0
73
10
0
% A
% Cys:
0
0
0
10
0
10
0
0
10
55
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
19
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
64
10
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
10
0
10
0
73
10
73
19
10
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
64
10
0
0
0
0
0
10
0
19
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
10
0
10
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
73
10
0
0
0
10
0
0
0
55
10
0
10
% R
% Ser:
0
10
0
19
0
0
0
64
0
10
10
0
0
10
0
% S
% Thr:
0
55
0
0
0
10
0
19
0
10
10
10
10
46
73
% T
% Val:
0
10
19
0
10
64
10
0
10
19
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _