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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DERL1
All Species:
35.45
Human Site:
S218
Identified Species:
48.75
UniProt:
Q9BUN8
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUN8
NP_001128143.1
251
28801
S218
P
S
R
R
G
G
V
S
G
F
G
V
P
P
A
Chimpanzee
Pan troglodytes
XP_001146267
206
23930
P191
F
F
L
M
F
R
Y
P
M
D
L
G
G
R
N
Rhesus Macaque
Macaca mulatta
XP_001099154
251
28812
S218
P
S
R
R
G
G
V
S
G
F
G
V
P
P
A
Dog
Lupus familis
XP_532320
251
28802
S218
P
S
R
R
G
G
V
S
G
F
G
V
P
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q99J56
251
28816
S218
P
S
R
R
G
G
V
S
G
F
G
V
P
P
A
Rat
Rattus norvegicus
XP_001071836
251
29075
S218
P
S
R
R
G
G
V
S
G
F
G
V
R
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511269
203
23348
G188
A
A
E
D
Q
P
G
G
G
G
R
H
N
W
G
Chicken
Gallus gallus
NP_001006350
251
28890
S218
P
N
R
R
G
G
V
S
G
F
G
I
P
P
A
Frog
Xenopus laevis
NP_001085401
251
28935
S218
P
S
R
R
G
G
V
S
G
F
G
V
P
P
A
Zebra Danio
Brachydanio rerio
NP_998609
256
29063
S218
P
N
R
R
G
G
V
S
G
F
G
V
P
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQ57
245
28238
G217
D
V
S
G
G
F
G
G
F
G
L
P
P
E
S
Honey Bee
Apis mellifera
XP_001122972
250
29184
R218
P
P
Q
R
G
N
I
R
W
F
G
S
V
P
I
Nematode Worm
Caenorhab. elegans
Q93561
245
28447
G217
D
E
D
G
G
I
H
G
Q
D
G
N
I
R
G
Sea Urchin
Strong. purpuratus
XP_797383
255
29542
S220
P
N
R
R
G
G
V
S
G
F
G
E
A
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q4G2J3
249
28426
Q227
D
D
N
V
V
V
A
Q
P
P
N
A
G
I
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZ96
244
28225
R227
D
E
P
V
V
I
A
R
P
E
D
V
R
F
A
Baker's Yeast
Sacchar. cerevisiae
Q12743
341
38112
P247
P
N
G
K
F
S
T
P
W
W
F
T
S
L
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82
99.5
99.1
N.A.
97.6
88
N.A.
77.6
91.2
86.4
84.7
N.A.
42.6
51.7
47.4
64.3
Protein Similarity:
100
82
99.5
99.5
N.A.
98.8
92
N.A.
79.2
96.8
93.2
91.4
N.A.
60.9
66.1
65.7
75.2
P-Site Identity:
100
0
100
100
N.A.
100
93.3
N.A.
6.6
86.6
100
86.6
N.A.
13.3
40
13.3
73.3
P-Site Similarity:
100
0
100
100
N.A.
100
93.3
N.A.
13.3
100
100
100
N.A.
20
53.3
13.3
86.6
Percent
Protein Identity:
N.A.
35
N.A.
31.4
23.1
N.A.
Protein Similarity:
N.A.
54.5
N.A.
51.3
36.9
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
0
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
6
0
0
0
0
12
0
0
0
0
6
6
0
48
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
6
6
6
0
0
0
0
0
12
6
0
0
0
0
% D
% Glu:
0
12
6
0
0
0
0
0
0
6
0
6
0
6
0
% E
% Phe:
6
6
0
0
12
6
0
0
6
59
6
0
0
6
0
% F
% Gly:
0
0
6
12
71
53
12
18
59
12
65
6
12
0
18
% G
% His:
0
0
0
0
0
0
6
0
0
0
0
6
0
0
0
% H
% Ile:
0
0
0
0
0
12
6
0
0
0
0
6
6
6
6
% I
% Lys:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
6
0
0
0
0
0
0
0
12
0
0
6
0
% L
% Met:
0
0
0
6
0
0
0
0
6
0
0
0
0
0
0
% M
% Asn:
0
24
6
0
0
6
0
0
0
0
6
6
6
0
6
% N
% Pro:
65
6
6
0
0
6
0
12
12
6
0
6
48
59
0
% P
% Gln:
0
0
6
0
6
0
0
6
6
0
0
0
0
0
0
% Q
% Arg:
0
0
53
59
0
6
0
12
0
0
6
0
12
12
0
% R
% Ser:
0
36
6
0
0
6
0
53
0
0
0
6
6
0
18
% S
% Thr:
0
0
0
0
0
0
6
0
0
0
0
6
0
0
0
% T
% Val:
0
6
0
12
12
6
53
0
0
0
0
48
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
12
6
0
0
0
6
0
% W
% Tyr:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _