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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DERL1 All Species: 36.97
Human Site: Y207 Identified Species: 50.83
UniProt: Q9BUN8 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BUN8 NP_001128143.1 251 28801 Y207 L S T P Q F L Y R W L P S R R
Chimpanzee Pan troglodytes XP_001146267 206 23930 G180 E L I G N L V G H L Y F F L M
Rhesus Macaque Macaca mulatta XP_001099154 251 28812 Y207 L S T P Q F L Y R W L P S R R
Dog Lupus familis XP_532320 251 28802 Y207 L S T P Q F L Y R W L P S R R
Cat Felis silvestris
Mouse Mus musculus Q99J56 251 28816 Y207 L S T P Q F L Y R W L P S R R
Rat Rattus norvegicus XP_001071836 251 29075 Y207 L S T P Q F L Y R W L P S R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511269 203 23348 S177 G F G V P P A S M R R A A E D
Chicken Gallus gallus NP_001006350 251 28890 Y207 L S T P Q F L Y R W L P N R R
Frog Xenopus laevis NP_001085401 251 28935 Y207 L S T P Q F L Y R W L P S R R
Zebra Danio Brachydanio rerio NP_998609 256 29063 Y207 L S T P Q F L Y Q M F P N R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQ57 245 28238 R206 E T P Q F L K R L V P D V S G
Honey Bee Apis mellifera XP_001122972 250 29184 E207 L N T P K I L E S Y F P P Q R
Nematode Worm Caenorhab. elegans Q93561 245 28447 R206 S T P E F L H R L I P D E D G
Sea Urchin Strong. purpuratus XP_797383 255 29542 Y209 L S T P Q F L Y K Y F P N R R
Poplar Tree Populus trichocarpa
Maize Zea mays Q4G2J3 249 28426 A216 K T P S F I K A L F A D D N V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VZ96 244 28225 A216 K T P S F L K A L F A D E P V
Baker's Yeast Sacchar. cerevisiae Q12743 341 38112 Y236 S R K A D P T Y G I S P N G K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82 99.5 99.1 N.A. 97.6 88 N.A. 77.6 91.2 86.4 84.7 N.A. 42.6 51.7 47.4 64.3
Protein Similarity: 100 82 99.5 99.5 N.A. 98.8 92 N.A. 79.2 96.8 93.2 91.4 N.A. 60.9 66.1 65.7 75.2
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 0 93.3 100 73.3 N.A. 0 40 0 73.3
P-Site Similarity: 100 6.6 100 100 N.A. 100 100 N.A. 6.6 100 100 86.6 N.A. 6.6 66.6 6.6 93.3
Percent
Protein Identity: N.A. 35 N.A. 31.4 23.1 N.A.
Protein Similarity: N.A. 54.5 N.A. 51.3 36.9 N.A.
P-Site Identity: N.A. 0 N.A. 0 13.3 N.A.
P-Site Similarity: N.A. 13.3 N.A. 13.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 6 0 0 6 12 0 0 12 6 6 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 6 0 0 0 0 0 0 24 6 6 6 % D
% Glu: 12 0 0 6 0 0 0 6 0 0 0 0 12 6 0 % E
% Phe: 0 6 0 0 24 53 0 0 0 12 18 6 6 0 0 % F
% Gly: 6 0 6 6 0 0 0 6 6 0 0 0 0 6 12 % G
% His: 0 0 0 0 0 0 6 0 6 0 0 0 0 0 0 % H
% Ile: 0 0 6 0 0 12 0 0 0 12 0 0 0 0 0 % I
% Lys: 12 0 6 0 6 0 18 0 6 0 0 0 0 0 6 % K
% Leu: 59 6 0 0 0 24 59 0 24 6 42 0 0 6 0 % L
% Met: 0 0 0 0 0 0 0 0 6 6 0 0 0 0 6 % M
% Asn: 0 6 0 0 6 0 0 0 0 0 0 0 24 6 0 % N
% Pro: 0 0 24 59 6 12 0 0 0 0 12 65 6 6 0 % P
% Gln: 0 0 0 6 53 0 0 0 6 0 0 0 0 6 0 % Q
% Arg: 0 6 0 0 0 0 0 12 42 6 6 0 0 53 59 % R
% Ser: 12 53 0 12 0 0 0 6 6 0 6 0 36 6 0 % S
% Thr: 0 24 59 0 0 0 6 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 6 0 0 6 0 0 6 0 0 6 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 42 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 59 0 12 6 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _