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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHD1
All Species:
8.18
Human Site:
S22
Identified Species:
12
UniProt:
Q9BUP0
Number Species:
15
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BUP0
NP_079478.1
239
26928
S22
R
R
E
E
A
E
E
S
G
P
Q
L
A
P
L
Chimpanzee
Pan troglodytes
XP_001143163
390
43806
S173
R
R
E
E
A
E
E
S
G
P
Q
L
A
P
L
Rhesus Macaque
Macaca mulatta
Q5TM25
147
16701
Dog
Lupus familis
XP_543290
141
15950
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4J1
240
26981
G25
V
R
A
E
T
D
Q
G
D
P
Q
P
A
P
C
Rat
Rattus norvegicus
Q4FZY0
239
26741
E19
R
R
L
Q
M
E
D
E
G
G
E
A
T
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518105
170
19250
N16
L
G
R
E
K
F
T
N
C
S
P
I
A
P
T
Chicken
Gallus gallus
NP_001026943
238
26908
S19
R
R
L
L
L
E
E
S
G
A
E
A
E
G
D
Frog
Xenopus laevis
NP_001085773
231
26398
N19
R
R
L
V
L
E
D
N
E
P
P
E
D
G
D
Zebra Danio
Brachydanio rerio
XP_683253
227
26230
N19
R
R
L
D
A
D
T
N
P
G
T
Q
D
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ26
217
25068
S18
S
N
K
D
S
V
D
S
P
S
S
T
T
N
T
Honey Bee
Apis mellifera
XP_624640
195
22857
E20
R
R
Q
R
I
N
D
E
L
E
E
G
K
D
V
Nematode Worm
Caenorhab. elegans
O16305
149
16806
Sea Urchin
Strong. purpuratus
XP_001176294
193
22506
E18
A
R
R
D
R
I
N
E
G
D
E
Q
G
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LQN4
166
18399
E12
V
S
K
K
L
D
E
E
Q
I
N
E
L
R
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P61859
149
16978
Conservation
Percent
Protein Identity:
100
61.2
23.8
53.1
N.A.
81.2
65.6
N.A.
51.4
74.4
69.4
63.5
N.A.
48.5
47.7
21.3
50.2
Protein Similarity:
100
61.2
38.4
57.7
N.A.
87.9
78.6
N.A.
61
84
83.2
80.7
N.A.
59.4
61.9
38.4
61.5
P-Site Identity:
100
100
0
0
N.A.
40
26.6
N.A.
20
40
26.6
20
N.A.
6.6
13.3
0
13.3
P-Site Similarity:
100
100
0
0
N.A.
53.3
46.6
N.A.
33.3
46.6
40
40
N.A.
33.3
40
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.9
N.A.
20.9
Protein Similarity:
N.A.
N.A.
N.A.
37.2
N.A.
38.9
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
19
0
0
0
0
7
0
13
25
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% C
% Asp:
0
0
0
19
0
19
25
0
7
7
0
0
13
13
13
% D
% Glu:
0
0
13
25
0
32
25
25
7
7
25
13
7
13
13
% E
% Phe:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
7
0
0
0
0
0
7
32
13
0
7
7
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
7
0
0
0
7
0
7
0
0
0
% I
% Lys:
0
0
13
7
7
0
0
0
0
0
0
0
7
0
0
% K
% Leu:
7
0
25
7
19
0
0
0
7
0
0
13
7
0
13
% L
% Met:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
7
7
19
0
0
7
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
13
25
13
7
0
25
0
% P
% Gln:
0
0
7
7
0
0
7
0
7
0
19
13
0
0
7
% Q
% Arg:
44
57
13
7
7
0
0
0
0
0
0
0
0
7
0
% R
% Ser:
7
7
0
0
7
0
0
25
0
13
7
0
0
0
7
% S
% Thr:
0
0
0
0
7
0
13
0
0
0
7
7
13
0
13
% T
% Val:
13
0
0
7
0
7
0
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _